$BGNE

BGNE intend to add to long term portfolio. No position yet untill market shows some strength

+Initiations 1/12: $AAP $ABBV $ASML $AZO $BGNE $CCB $COST $DLTR $FITB $FIVE $FNWD $FVRR $FWRG $GNTA $HBAN $HD $HTZ $IFF $KEY $LOW $MTB $MTCH $ORLY $RGF $RIOT $SSU $STM $TGT $TSCO $UPWK

Largest stocks that hit new 52 Week Lows at some point today AT&T $T Medtronic $MDT HDFC $HDB Block (Square) $SQ Snapchat $SNAP Zoom $ZM $NIO Carvana $CVNA Match $MTCH $BBDO Barrick $GOLD BeiGene $BGNE $ROKU Zimmer $ZBH Southwest $LUV Pinterest $PINS Credit Suisse $CS $PATH

+Initiations 10/12: $ACT $AMP $BGNE $CFLT $DNA $EARN $EFTR $FREY $ISOS $LIFE $LTRX $NKE $PENN $REPH $RSI $SBSW $TM $VRDN $ZH . -Initiations 10/12: $DKNG

Monday, October 11, 2021 U.S. stock futures are edging lower ahead of the Columbus Day holiday, with oil prices extending last week gains and moving to fresh 7-year highs ahead of key inflation data later this week and the upcoming earnings season, which starts Friday with the big banks ($JPM, $Citi). Over the weekend, Goldman Sachs cuts its 2021 economic growth forecast by 10 basis points, to 5.6%, while lowering its 2022 estimate by 40 basis point to 4% citing a “longer lasting virus drag on virus-sensitive consumer services” and the impact of an extended shortage in global semiconductors. The bond market is closed today in observance of the Columbus Day holiday after the 10-year yield closed at 1.612% on Friday, the highest level of the week. Oil prices extending gains, as WTI crude rises over $2.20 or 2.8% above $81.50. In Asian markets, The Nikkei Index rose 449 points (1.6%%) to 28,498, the Shanghai Index was little changed at 3,591, and the Hang Seng Index jumped nearly 2% or 487 points to settle at 25,325. In Europe, the German DAX is down about -50 points to 15,150, while the FTSE 100 is up about 0.25% at 7,110. Q quiet day expected ahead with no economic data and bond markets closed. Market Closing Prices Yesterday · The S&P 500 Index dropped -8.42 points, or 0.19%, to 4,391.34 · The Dow Jones Industrial Average fell -8.69 points, or 0.03%, to 34,746.25 The Nasdaq Composite slid -74.48 points, or 0.51%, to 14,579.54 · The Russell 2000 Index declined -17.00 points, or 0.76% to 2,233.09 Events Calendar for Today · No Major Economic Data Earnings Calendar: · Earnings Before the Open: AZZ, ENZ, FAST · Earnings After the Close: PNFP, SGH Other Key Events: · American Society of Retina Specialists Annual Scientific Meeting, in San Antonio, TX 10/8-10/12 World News · Goldman Sachs cuts its forecast for U.S economic growth over the weekend, citing a “longer lasting virus drag on virus-sensitive consumer services” and the impact of an extended shortage in global semiconductors. Goldman trimmed its 2021 growth forecast by 10 basis points, to 5.6%, while lowering its 2022 estimate by 40 basis point to 4%, adding that consumer spending is likely to be held back by pandemic uncertainty and a softer-than-expected fiscal response from the Biden administration. · Taiwan will keep bolstering its defenses to ensure nobody can force them to accept the path China has laid down that offers neither freedom nor democracy, President Tsai Ing-wen said on Sunday – Reuters Sector News Breakdown Consumer · Southwest Airlines ($LUV) cancelled 808 flights yesterday and has cancelled another 1,006 today, according to data from Flightaware.com. The company blamed the disruption on air traffic control issues and weather, although other major airlines are not delaying or cancelling flights at an elevated rate. There was speculation that some Southwest employees have called in sick in a form of protest over the mandatory vaccination rules in place, which have been unconfirmed · Hasbro ($HAS) said CEO Brian Goldner will take a medical leave of absence, effective immediately, slightly more than a year after disclosing that he was undergoing continued medical care following treatment for cancer in 2014. Energy, Industrials and Materials · Honeywell ($HON) raised its business outlook for jet deliveries on Sunday as travel restrictions ease as they now see 7,400 new business jet deliveries worth $238 bln over the next 10 years, up 1% from the same 10-year forecast a year ago. Business jet operators surveyed by Honeywell reported a sharp increase in their used jet purchase plans, 12% above last year’s report · Emerson Electric ($EMR) plans to merge two of its software businesses with Aspen Technology (AZPN) in a roughly $11B deal that values Aspen at around $160 a share, as shareholders would receive $87 and 0.42 share of the combined company for each share they currently own – WSJ https://on.wsj.com/3FxyVx7 · Cleveland-Cliffs ($CLF) agrees to acquire Ferrous Processing and Trading, one of the largest processors and distributors of prime ferrous scrap in the U.S., in a deal with an enterprise value of ~$775M. · Tutor Perini’s ($TPC) joint-venture signed a contract valued at ~$178 million by the U.S. Department of the Interior, Bureau of Reclamation, for the Friant-Kern Canal Middle Reach Capacity Correction Phase I project in central California, southeast of Visalia. Financials · Prudential ($PRU) mentioned positively in Barron’s saying for many years, Prudential Financial’s stock had a nice yield, but it didn’t offer much capital appreciation. The pandemic didn’t help, as the shares lost about 12% last year, dividends included, versus an 18% return for the S&P 500 index. But the market has changed its view, partly owing to an uptick in rates. On top of that, Prudential, whose businesses include life insurance, variable annuities, and asset management, is getting some credit for more-consistent earnings in recent years. Healthcare · Supernus Pharmaceuticals, Inc. ($SUPN) to acquire Adamas Pharmaceuticals, Inc. (ADMS) through a tender offer for $8.10 per share in cash (or an aggregate of approximately $400 million), payable at closing plus two non-tradable contingent value rights (CVR) collectively worth up to $1.00 per share in cash (or an aggregate of approximately $50 million), for a total consideration of $9.10 per share in cash (or an aggregate of approximately $450 million). · AstraZeneca ($AZN) Phase 3 trial met its primary end point; trial showed a reduced risk of death & severe C-19 by 67% in a trial where 90% of participants were from high-risk categories; only long acting antibody combination that can both prevent & treat C-19 · Merck ($MRK) submitted an Emergency Use Authorization (EUA) application to the U.S. FDA for molnupiravir, an investigational oral antiviral medicine, for the treatment of mild-to-moderate COVID-19 who are at risk for progressing to severe COVID-19 and/or hospitalization · Regenxbio ($RGNX) announces initial data from the ongoing Phase II ALTITUDE trial of RGX-314 for the treatment of diabetic retinopathy (DR) without center-involved diabetic macular edema (CI-DME) using in-office suprachoroidal delivery. · BeiGene ($BGNE) announced that BRUKINSA has been approved in Australia for the treatment of adult patients with mantle cell lymphoma who have received at least one prior therapy Technology, Media & Telecom · Apple ($AAPL) asked a federal appeals court on Friday to throw out a legal decision that would require the tech giant to tweak its strict App Store rules and force it to allow app developers to inform customers of ways to pay for subscriptions and services outside the App Store – NYT · Gray Television ($GTN) a positive mention in Barron’s saying at about $23.50 a share, it has a price/earnings ratio of five based on 2022 estimates. It looks like an inexpensive way to bet on broadcast as Gray’s strength in local news helps it make a killing in political ads · Toshiba Corp ($6502.T) said it would announce the results of a strategic review of its business along with its quarterly earnings results and a new mid-term business plan on Nov. 12. A spokesperson said the results of Toshiba’s strategic review would be part of the new business plan. The company had previously said the review would be announced this month. · U.S.-listed Chinese tech stocks Alibaba ($BABA), JD.com ($JD) and Baidu ($BIDU) among market leaders early; BABA shares up over 5% after Reuters noted the Daily Journal Corp, chaired by Berkshire Hathaway Vice Chairman Charlie Munger, boosted its holdings in BABA by 83% during Q3, according to public disclosures. Also helping sentiment in China listed stocks, China’s antitrust regulator also fines delivery giant Meituan 3.4 bln yuan ($527.4 mln), a smaller than expected figure, for abusing its dominant market position · Comcast ($CMCSA) downgraded to Market Perform from Outperform at Raymond James

Friday, October 8, 2021 Futures Up/Down % Last Dow 42.00 0.12% 34,678 S&P 500 2.50 0.06% 4,392 Nasdaq 0.00 0.00% 14,881 After a week of overnight swings and market volatility, U.S. futures come into Friday’s trading looking flat, with the S&P little changed at 4,390 after a strong session on Thursday was met with a late day pullback, as major averages finished well off their best levels. U.S. futures steady as investors anticipate a key employment report that could offer clues on the Fed’s timeline for reducing bond purchases. Nonfarm payroll data at 8:30 AM with an est. for +500K jobs added, private payrolls est. +455K, manufacturing payrolls +25K and the unemployment rate to fall to 5.1% from 5.2%; average hourly earnings expected to rise +0.4% (vs. last month +0.6%). Equities rose and Treasuries sank on Thursday after Senate leaders pulled the U.S. from the brink of default with a deal for a short-term debt ceiling increase in the amount of $480B to a $28.9 trillion debt limit. However, this could be short lived as the agreement only funds Treasury debt until Dec. 3, meaning Senators will again face a deadline for default. In Asian markets, the Shanghai Index opened for trading after a week long pause to celebrate its Golden Week holiday, rising 24 points to 3,592, the Hang Seng Index gained 136 points to 24,837 and the Nikkei advanced 370 points (1.34%) to 28,048. In Europe, the German DAX is down a few points at 15,235, while the FTSE 100 is up a few at 7,085. Oil prices are higher, heading for its seventh weekly gain with WTI crude nearing $80 Market Closing Prices Yesterday The S&P 500 Index gained 36.21 points, or 0.83%, to 4,399.76 The Dow Jones Industrial Average rose 337.95 points, or 0.98%, to 34,754.94 The Nasdaq Composite surged 152.10 points, or 1.05%, to 14,654.02 The Russell 2000 Index advanced 35.14 points, or 1.59% to 2,250.09 Events Calendar for Today 8:30 AM ET Non-Farm Payrolls for September…est. +500K 8:30 AM ET Private Payrolls for September…est. +455K 8:30 AM ET Manufacturing Payrolls for September…est. +25K 8:30 AM ET Unemployment Rate for September…est. 5.1% 8:30 AM ET Average Hourly Earnings for September…est. +0.4% 10:00 AM ET Wholesale Inventories MoM for Aug 1:00 PM EST Baker Hughes Weekly rig count data Macro Up/Down Last Nymex 0.58 78.86 Brent 0.65 82.60 Gold 0.90 1,762.00 EUR/USD 0.0014 1.1563 JPY/USD 0.23 111.82 10-Year Note +0.021 1.593% World News The U.S. Senate on Thursday approved legislation to temporarily raise the federal government’s $28.4 trillion debt limit and avoid the risk of a historic default this month, but it put off until early December a decision on a longer-lasting remedy. German Aug Trade Balance smaller surplus: +€13.0b vs +€15.8b consensus; German August Exports lower down -1.2% vs +0.5% consensus and German Aug Imports higher rising +3.5% vs 1.8% consensus Sector News Breakdown Consumer Home Depot ($HD) and Lowe’s ($LOW) both downgraded to Hold from Buy at Loop Capital Tesla ($TSLA) CEO Elon Musk confirmed that the car maker is moving its headquarters from Fremont, California to Austin, Texas, where the company has been constructing a new factory for a little over a year. CEO Musk also said a global shortage of chips and ships is the only thing standing in the way of the company maintaining sales growth in excess of 50% Oatly Group ($OTLY) upgraded to Overweight from Neutral with a $21 price target Drive Shack ($DS) reports prelim Q3 revs of $75M vs. est. $76.74M Scientific Games ($SGMS) wins 10-year Vermont lottery systems contract; company’s advanced platforms and game services will modernize lottery play and maximize revenues for programs in green mountain state Thor Industries ($THO) increases regular quarterly dividend 5% to 43c per share Energy, Industrials and Materials Dow Transports finished the day down -0.25% just above the 14,500 level, but slipping below its 50-day MA at 14,515 B. Hunt ($JBHT) downgraded to Underweight on relative valuation at JPMorgan Union Pacific ($UNP) upgraded to Overweight from Neutral with a price target of $247, up from $234 at JPMorgan on recent selloff Sundial Growers Inc. ($SNDL) announced it will acquire liquor and pot retailer Alcanna in an all-stock deal with a total consideration of about C$346M Financials Pzena Investment Management Inc. ($PZN) prelim AUM as of Sept 30 of $50.8 bln Chubb ($CB) announced a definitive agreement to acquire the life and non-life insurance companies that house the personal accident, supplemental health and life insurance business of Cigna (CI) in seven Asia-Pacific, or APAC, markets for $5.75B in cash Healthcare Accolade Inc. ($ACCD) Q2 revs $73.3M vs. est. $70.4M; Q2 adj Ebitda loss (-$19.4M) vs. est. loss (-$21.9m); sees FY revs $303M-$307M, from prior view $300M-$305M (est. $303.4M); guides Q3 adj Ebitda loss $21.5M-$24.5M vs. est. loss $20.2M, but Q3 revs above views Quidel ($QDEL) guides Q3 revs $505M-$510M vs. est. $186.3M; says covid-19 revenues for Q3 of 2021 expected to be about $406M, compared with $375.7M YoY Allogene Therapeutics ($ALLO) shares fall over 35% after reporting the FDA put a clinical hold of Allocar T trials based on a single patient case in alpha2 trial; believes data from alpha trials demonstrates a favorable clinical profile of allo-501a Apollo EndoSurgery ($APEN) sees 3Q revs $16-16.4Mm vs est. $14.4Mm; sees 3Q net loss $6.1-7.3Mm vs est. net loss $8.3Mm BeiGene’s ($BGNE) BRUKINSA (zanubrutinib) has been approved in Australia for the treatment of adult patients with Waldenström’s macroglobulinemia who have received at least one prior therapy or in first line treatment for patients unsuitable for chemo-immunotherapy. Mirati Therapeutics ($MRTX) to collaborate with Sanofi ($SNY) on phase 1/2 study evaluating combination of adagrasib with a SHP2 inhibitor in KRAS g12c-mutated lung cancer Nkarta ($NKTX) provided updates on its NKX019 and NKX101 clinical development programs saying patients have been dosed in the international phase 1 trial of NKX019 in advanced B-cell malignancies IsoPlexis (ISO)333M share IPO priced at $15.00 Pyxis Oncology ($PYXS)5M share IPO priced at $16.00 Prelude Therapeutics ($PRLD) shares fall after announces presentation of encouraging data from multiple programs at the AACR-NCI-EORTC virtual international conference on molecular targets and cancer therapeutics Relay Therapeutics ($RLAY) announces interim clinical data for RLY-4008, in a first-in-human trial in patients with FGFR2-altered cholangiocarcinoma and multiple other solid tumors Technology, Media & Telecom VMware ($VMW) authorized new stock buyback program for up to $2B Samsung Electronics Co Ltd ($SSNLF) said Q3 operating profit likely jumped 28% to its highest in three years, helped by rising memory chip prices and brisk sales of its new foldable smartphones; estimated July-September profit at 15.8 trillion won ($13.3 billion) vs. est. of 16.1 trillion won. ChipMOS (IMOS) reports Q3 revenues rose 25.9% on a Y/Y basis to $257.2M (+2.6% Q/Q) vs. a consensus of $262.90M. Taiwan Semiconductor Manufacturing Co.’s ($TSM) September revenue was up 19.7% Y/Y to NT$152.69B or about $5.44B. AU Optronics ($AUOTY) reports September revenue rose 26.5% Y/Y to NT$33.0B (+0.9% M/M); Q3 revenues rose 35.3% Y/Y NT$99.05B Oracle ($ORCL), Telecom Italia, and Noovle, TIM Group’s cloud company, have signed a collaboration agreement to offer multi-cloud services for enterprises and the public sector organizations in Italy. Sirius XM ($SIRI) downgraded to Neutral from Overweight with a price target of $7, down from $8 at JPMorgan

$PSNL Announces Collaboration with MapKure (jointly owned by $BGNE & $SWTX) to Use Personalis’ NeXT Platform for Clinical Trials and Companion Diagnostic Development

DCR % Screen 581 names eod with these showing RS new high : TUP NSC FCX SAM CNI NUAN DE SHW EXPD FMC RBC PENN NUS CP DKS AAWW HZNP NVCR TRIL SQM ALB ZG Z APPS CC DNLI TPTX BEPC BGNE IRTC MAXR DKNG WKHS SWAV CARR SILK

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