$CRSP

$CLF Nov 17 C $AA Nov 27 C $MSOS Nov10 5.5 C $COMM Nov 1.5 C $WFC Jan 40 C $Z Jan 50 C $ETN Nov 220 C $TEVA Nov 9.5 C $ZI Nov 12.5 P $TSLA Mar 100 P $MU Dec 65 P $CRSP Nov03 38 P $BP Nov03 37 P $COMM Nov 1.5 C $XRX Dec 11 P $AES Dec 12 P $AAL Jun 11 P $VNET Mar 2 P

$CLF Nov 17 C $AA Nov 27 C $MSOS Nov10 5.5 C $COMM Nov 1.5 C $WFC Jan 40 C $Z Jan 50 C $ETN Nov 220 C $TEVA Nov 9.5 C $ZI Nov 12.5 P $TSLA Mar 100 P $MU Dec 65 P $CRSP Nov03 38 P $BP Nov03 37 P $COMM Nov 1.5 C $XRX Dec 11 P $AES Dec 12 P $AAL Jun 11 P $VNET Mar 2 P

A staddle could be an option, will likely move hard one way or the other based on FDA meeting tomorrow on $CRSP drug > @dramdram said: wonder if $CRSP is worth s shot this week

wonder if $CRSP is worth s shot this week

2750 $CRSP OCT2023 $65 Cs trade 4.8

$CRSP oct 65C UOA

that is bull CRSP buy

2750 $CRSP Oct23 65.0 Calls trade $4.85 (CboeTheo=4.66) ASKSIDE [ARCA] IV=61.5% +4.3 FLOOR - OPENING Vol=3532, OI=1408

+Initiations 5/30: $BDX $CFLT $CRSP $EW $HGBL $JNJ $KVUE $NARI $SGHT $SLRN $VRDN $VRTX . -Initiations 5/30: $EMBC

Upgrades 4/13: $BX $CFRX $CVX $DKNG $EOG $INGR $MNTK $MRK $NVO $SHOO $SPWR $VFC $WWE .. Downgrades 4/13: $BRFS $CUBE $FSLR $JD $LSI $LXU $LYB $NATI $NSA $PKX $PLTK $SPWH $TESS $TRTN $XOM +Initiations 4/13: $AVGO $CCCS $COST $CRSP $ENPH $FTCI $MGNI $NTLA $PLRX $PRI $PUBM $RLAY $RXST $SEDG $SNAL $VERV .. -Initiations 4/13:

👀 $clnn $evtl $veru $amc $crsp $mara $rytm

CRSP dropped from $72's to $62's in 10 minutes, now bouncing a bit...

2000 $CRSP Jun22 24th 80.0 Calls $2.85 (CboeTheo=2.41) ASKSIDE AMEX IV=98.3% +15.6 MPRL 31 x $1.90 - $2.90 x 32 PHLX FLOOR - OPENING Vol=2002, OI=18

CRSP to dangerous for me.... who knows wether that stuff ever works, i believe its rumoured it can change a lot of unintended DNA

Cathy owns a lot of crsp. probably half the move lol

whatever happened to $crsp

+Initiations 2/14: $ANET $BCTX $CIEN $CRBU $CRSP $CSCO $DIDI $FFIV $GSM $IMGO $JNPR $LBPH $LTRX $PRCH $QRHC $RBLX $SMRT $ZM . -Initiations 2/14: $DBRG

**@charliebilello:** 2020 | 2021 Returns...$PTON: +434% | -74%$ZM: +396% | -44%$PINS: +254% | -42%$TWLO: +244% | -20%$PENN: +238% | -42%$Z: +183% | -52%$CRSP: +151% | -51%$ROKU: +148% | -29%$TDOC: +139% | -52%$CHGG: +138% | -69%$SFIX: +129% | -67%$STNE: +110% | -78%$SPCE: +105% | -34% https://twitter.com/charliebilello/status/1469325748116807680

GM all > @CarlosH said: Cathie Wood's ARK Invest Posts Fund Purchases For Tuesday, Nov. 23, 2021: $ZM, $EXAS, $CRSP, $NVTA, $MTLS, $VLD, $ACHR, $MKFG, $NIU, $MNDY, $GENI, $ROKU, $HOOD, $NNDM, $CND, $VUZI, $ADPT, $PACB, $SDGR, $BFLY, $BNR, $SURF, $DKNG, $STNE, $TOST, $PLTR

Cathie Wood's ARK Invest Posts Fund Purchases For Tuesday, Nov. 23, 2021: $ZM, $EXAS, $CRSP, $NVTA, $MTLS, $VLD, $ACHR, $MKFG, $NIU, $MNDY, $GENI, $ROKU, $HOOD, $NNDM, $CND, $VUZI, $ADPT, $PACB, $SDGR, $BFLY, $BNR, $SURF, $DKNG, $STNE, $TOST, $PLTR

RECAP 10/14 Chatter (1/2) $SAVA - NIH investigating $HZAC + $DKNG Investment $MSFT -/+ US Army Pauses AR goggles, still committed $CRSP + Sale Chatter $MRNA $PFE $BNTX $NVAX $AZN - Biden Vaccine IP waivers

out 100% at $4 > @kooleraid said: L CRSP 95c $2 quick dip toe or fuck off

CRSP we up +50% birdies

L CRSP 95c $2 quick dip toe or fuck off

CRSP lol lol cathy likin that dildo again

Wednesday, October 13, 2021 Futures Up/Down % Last Dow 34.00 0.10% 34,295 S&P 500 5.75 0.14% 4,346 Nasdaq 61.75 0.42% 14,715 U.S. futures recover from overnight losses ahead of Dow component JPMorgan earnings and inflation data later this morning (CPI), reversing overnight losses despite weakness in Dow component Apple (AAPL), which is down about -0.5% after reports it expects to make 10 million fewer iPhone than planned and is poised to slash iPhone production goal due to chip crunch. Oil prices and Treasury yields decline, while gold rises ahead of a key reading of consumer price September inflation. Futures are getting a boost after better economic data in China as September exports rose 28.1% from last year as consumer demand outpace supply chain disruptions and power shortages, while last night’s passage of a debt ceiling extension by House lawmakers puts at least one market concern to the side until early December. In Asian markets, The Nikkei Index fell -90 points to 28,140, the Shanghai Index rose 14 points to 3,561 and the Hang Seng Index was closed. In Europe, the German DAX is up over 100 points to 15,250, while the FTSE 100 is slightly lower at 7,120. U.S. stocks ended lower following a choppy session on Tuesday, with investors nervous about upcoming third-quarter earnings reports. In addition to the CPI data, the Federal Reserve will release minutes from its last policy meeting, and investors are looking for further clues on when the central bank could begin tapering its bond-buying program. Market Closing Prices Yesterday The S&P 500 Index dropped -10.54 points, or 0.24%, to 4,350.65 The Dow Jones Industrial Average fell -117.72 points, or 0.34%, to 34,378.34 The Nasdaq Composite slipped -20.28 points, or 0.14%, to 14,465.92 The Russell 2000 Index advanced 13.63 points, or 0.61% to 2,234.27 Events Calendar for Today 7:00 AM ET MBA Mortgage Applications Data 8:30 AM ET Consumer Price Index (CPI) Headline MoM for September…est. +0.3% 8:30 AM ET CPI Core: Ex Food & Energy MoM for September…est. +0.2% 8:30 AM ET Consumer Price Index (CPI) Headline YoY for September…est. +5.3% 8:30 AM ET CPI Core: Ex Food & Energy YoY for September…est.+4.0% 10:30 AM ET Weekly DOE Inventory Data 4:30 PM ET API Weekly Inventory Data Earnings Calendar: Earnings Before the Open: AYR, BLK, DAL, JPM, SOTK Earnings After the Close: ETWO, ODC Other Key Events: China CPI, PPO for September Macro Up/Down Last Nymex -0.56 80.08 Brent -0.60 82.82 Gold 11.60 1,772.80 EUR/USD 0.0034 1.1562 JPY/USD -0.04 113.56 10-Year Note -0.015 1.565% World News China September exports rose1% from last year as consumer demand outpace supply chain disruptions and power shortages Japanese Core Machine Orders (M/M) Aug: -2.4% (exp 1.4%; previous 0.9%); Core Machine Orders (Y/Y) Aug: 17.0% (exp 13.9%; previous 11.1%) The House on Tuesday voted along party lines to raise the U.S. borrowing limit into December, as Democratic lawmakers wrestled with how to set a new ceiling for U.S. debt later this year over Republican resistance. Sector News Breakdown Consumer Duckhorn Portfolio Inc ($NAPA) said selling stockholders are offering 12 mln shares of common stock Monster Beverage ($MNST) downgraded to Hold from Buy at Jefferies Energy, Industrials and Materials International Paper ($IP) announces up to $2B share repurchase program Boeing ($BA) is the latest federal contractor to mandate COVID-19 vaccinations for all employees by December 8 under the Biden administration’s new rules saying its 125K U.S. employees must show proof of vaccination or have an approved religious or medical exemption by the deadline. Yesterday, Chicago soybean futures fell to the lowest level in nearly a year following a U.S. Department of Agriculture report that showed larger than expected yields of soybeans and corn; the USDA showed an uptick of nearly 100M bushels to U.S. corn ending stocks Glencore Plc ($GLNCY) said that it had reached an agreement to sell its zinc business in Bolivia to Canada’s Santa Cruz Silver Mining for some $110M Rattler Midstream LP ($RTLR), a subsidiary of Diamondback Energy, Inc. (FANG) announces strategic midland basin gas gathering & processing joint venture; invested approximately $104 mln in cash to acquire a minority interest in joint venture Vistra ($VST) announces $2 billion share repurchase program Gran Tierra Energy Inc. ($GTE) said that Q3 production grew 53% and that it expects the gains to continue in Q4; said it has produced an average of 28,957 barrels of oil a day in the quarter, compared with 18,944 barrels a day in the prior year period and 23,035 barrels a day QoQ Greenbrier ($GBX) announced the acquisition of more than 3,600 railcars, a portion of which will be held in GBX Leasing Financials BlackRock ($BLK) Q3 adj EPS $10.95 vs. est. $9.35; Q3 revs $5.05B vs. est. $4.9B; qtrly long-term net inflows of $98 billion; assets under management at qtr-end were $9.46 trillion vs $7.81 trillion at end of Q3 AvidXchange ($AVDX)64M share IPO price $25.00 AllianceBernstein L.P. ($AB) preliminary assets under management decreased to $742 billion during September 2021 from $761B at the end of August. Firmwide net inflows were outweighed by market depreciation, resulting in a 2% decline in AUM. In the month of September, net inflows to Retail and Private Wealth were partially offset by net outflows from Institutions. Ellington Financial Inc ($EFC) commenced an underwritten public offering of 5 mln shares of common stock RenaissanceRe Holdings Ltd. ($RNR) estimates that losses from certain 2021 catastrophe events will have a net negative impact of approximately $725 million on the Company’s Q3 results of operations Manning & Napier ($MN) preliminary assets under management (AUM) of $22B for September, compared with $22.7B as of Aug.31. Healthcare Sarepta ($SRPT) announces $500M common stock offering and guiding Q3 revs about $166.9M vs. est. $172M; had approximately $1.6 bln in cash, cash equivalents and investments as of September 30, 2021 CRISPR Therapeutics ($CRSP) shares slipped after announcing updated results from the company’s early-stage trial of its CAR-T cell therapy CTX110 as two patients in the phase 1 trial experienced Grade 3 or higher infections, with one patient having HHV-6 encephalitis, and another developing pseudomonal sepsis that resolved in four days. CytoSorbents ($CTSO) receives full FDA investigational device exemption approval to begin U.S. star-d trial on apixaban and rivaroxaban removal by the DrugSorb-ATR™ antithrombotic removal system during urgent cardiothoracic surgery Homology Medicines ($FIXX) announced the pheEDIT Phase 1 clinical trial for HMI-103, a one-time, in vivo product candidate that utilizes a gene editing approach for phenylketonuria, or PKU, based on the investigational new drug application, or IND, clearance from the FDA Apollo EndoSurgery ($APEN)4M share Spot Secondary priced at $7.75 Bicycle Therapeutics ($BCYC)24M share Secondary priced at $54.00 Relay Therapeutics ($RLAY)21M share Secondary priced at $26.50 Biogen ($BIIB) announces results of a new analysis of immune response to the COVID-19 vaccine among people with multiple sclerosis (MS). Teva Pharmaceuticals Europe BV, a European affiliate of Teva ($TEVA) presents new analyses of the COBRA study, which concluded no evidence was found to suggest that infants were adversely affected by maternal exposure to glatiramer acetate (GA) during pregnancy and breastfeeding with use of COPAXONE Technology, Media & Telecom Apple ($AAPL) suppliers Broadcom ($AVGO), Texas Instruments ($TXN) struggling to deliver enough chips; Apple expects to make 10 million fewer iPhone than planned and is poised to slash iPhone production goal due to chip crunch – Bloomberg (watch shares of $AAPL suppliers including $CRUS, $QRVO, $STM, $AVGO, $SWKS) SAP AG ($SAP) raised its 2021 projections for non-IFRS cloud revenue at constant currencies to range from EUR9.4B to EUR9.6B, up from its earlier view of EUR9.3 billion and EUR9.5 billion; also boosts cloud and software revenue at constant currencies view to EUR23.8 billion to EUR24.2 billion from its earlier view of EUR23.6 billion to EUR24 billion. Qualcomm ($QCOM) announces new $10.0 billion stock repurchase authorization IAC Inc. ($IAC) reports September Angi Inc. total revenue up 18% from last year with Dotdash revenue up 25%, and its Search business revenue up 74% from last year and Emerging & Other revenue was up 33% from last year Vimeo Inc ($VMEO) total revenue for September 2021 up 33%; subscribers for September 2021 up 14%; ARPU for September 2021 up 16% Smart Global Holding ($SGH) Q4 adj EPS $2.16 vs. est. $1.60; Q4 revs $467.7M vs. est. $461.3M; sees Q1 adj EPS $1.80-$2.20 vs. est. $1.49; sees Q1 revenue $440M-$480M vs. est. $458.55M; GAAP gross margin of 25.2%, up 620 basis points versus the year ago quarter and non-GAAP gross margin of 26.4%, up 690 basis points versus the year ago quarter VOXX International ($VOXX) 2Q EPS $0.01 vs est. $0.07 on sales $143.1Mm vs est. $134.4Mm

good day FB +100% CRSP +50%

closed CRSP +50%

CRSP looking good for a b/o

250 $CRSP JAN2022 $170 Cs trade 11.2

Apart from WMT and NIO I have two BIG winner today. CRSP and EDIT. Both bought on 6/7 at the bottom. CRSP 7/16 130 C from 3.9 to 39.

nothing of much note today...could keep going, I'd wait for a little consolidation though  > @RohanG said: @dros do you some flow for $crsp? or its already too high

@dros do you some flow for $crsp? or its already too high

$ARKK at $130 of $CRSP bump

slightly overbought so may need a quick rest > @ivtrades-Chris said: $CRSP back in the saddle

$CRSP back in the saddle

/*============================================= = Monday, June 14, 2021 = =============================================*/ Futures Up/Down % Last Dow 13.00 0.04% 34,370 S&P 500 4.50 0.11% 4,241 Nasdaq 45.75 0.33% 14,031 U.S. stocks futures are looking higher, as the S&P 500 looks to build on last week’s new all-time highs as investors and markets prepare for the Federal Reserve monetary policy meeting later this week. The S&P 500 posted its second consecutive record closing high on Friday with investors assessing the Federal Reserve’s stance that inflation spikes will prove to be transitory. For the week, the Dow fell 0.8%, the S&P 500 ticked up 0.4%, and the Nasdaq jumped 1.8%. Looking ahead this week, the big focus remains the Federal Reserve’s June policy decision and press conference Wednesday afternoon hoping to clarify the path forward for monetary policy as investors contemplate the staying power of higher inflation. Currently, the Federal Reserve is conducting these purchases at a rate of $120 billion per month, with this quantitative easing having served as a key tool the Fed used to provide support and liquidity to the economy during the pandemic. A number of key economic data releases are also scheduled for this week, including May retail sales. The yield on the benchmark 10-year Treasury inched up to around 1.464% after hitting a three-month low last Thursday In Asian markets, The Nikkei Index rose 213 points to 29,161, the Shanghai Index was closed the Hang Seng Index was also closed. In Europe, the German DAX rises over 35 points to 15,730, while the FTSE 100 gains 30 points to 7,170. Crypto assets are looking higher to start the week after Tesla (TSLA) tweeted about Bitcoin: This is inaccurate. Tesla only sold ~10% of holdings to confirm BTC could be liquidated easily without moving market. When there’s confirmation of reasonable (~50%) clean energy usage by miners with positive future trend, Tesla will resume allowing Bitcoin transactions. Oil prices are higher and gold prices are markedly lower. Market Closing Prices Yesterday The S&P 500 Index climbed 8.26 points, or 0.19%, to 4,247.44 The Dow Jones Industrial Average rose 13.40 points, or 0.04%, to 34,479.60 The Nasdaq Composite jumped 49.12 points, or 0.35%, to 14,069.42 The Russell 2000 Index advanced 24.40 points, or 1.06% to 2,335.81 Events Calendar for Today No Major U.S. Economic Data Earnings Calendar: Earnings Before the Open: MPAA Earnings After the Close: ELTP, MMMB, RFIL Other Key Events: Citigroup European Healthcare Conference (virtual), 6/14-6/16 European Hematology Association (EHA) Virtual Meeting, 6/9-6/17 FBN Securities Valley tech Tour (virtual), 6/14-6/15 Macro Up/Down Last Nymex 0.57 71.48 Brent 0.67 73.36 Gold -20.85 1,856.65 EUR/USD 0.0004 1.2113 JPY/USD 0.04 109.70 10-Year Note +0.002 1.464% World News G7 will donate 1 bln doses by next year, leaders agreed to language condemning Russia for destabilizing behavior, called on China to respect human rights and fundamental freedoms, will carry on talks on recent finance ministers agreement on tax NATO leaders are expected to brand China a security risk to the Western alliance on Monday, a day after the Group of Seven rich nations issued a statement on human rights in China and Taiwan that Beijing said slandered its reputation. With allied leaders also raising concerns about Russia’s recent military build-up near Ukraine, NATO Secretary-General Jens Stoltenberg described the summit, the first Joe Biden will attend as U.S. president, as a “pivotal moment” – Reuters Sector News Breakdown Consumer Tesla Inc ($TSLA) CEO Elon Musk tweeted on Sunday that the electric car marker will resume allowing bitcoin transactions when miners who verify transactions use more renewable energy. “When there’s confirmation of reasonable (~50%) clean energy usage by miners with positive future trend, Tesla will resume allowing Bitcoin transactions,” he said in a tweet. Energy, Industrials and Materials Royal Dutch Shell (RDS/A) is reviewing its holdings in the largest U.S. oil field for a potential sale, people familiar with the matter told Reuters. The sale could be for part or all of Shell’s position in the U.S. Permian Basin, which accounted for around 6% of the Anglo-Dutch company’s total oil and gas output last year. The holdings could be worth more than $10 billion Petrobras ($PBR) says it plans to sell its remaining 37.5% stake in fuel distributor BR Distribuidora in a follow-on public offering Lumber futures posted their biggest-ever weekly loss, extending a tumble from all-time highs reached last month as sawmills ramp up output and buyers hold off on purchases. Prices fell 18% this week, and has now dropped almost 40% from the record high reached on May 10 Iran said it has reached a broad agreement with the U.S. over the lifting of sanctions on its industrial sectors, including energy, but warned there was “very little time left” for world powers to revive a 2015 nuclear deal Financials Equinix Inc ($EQIX) said it signed agreements for additional joint ventures with Singapore’s sovereign wealth fund GIC to add $3.9 billion to expand a data center program. As per the terms, GIC will own an 80% equity interest in future joint ventures, and Equinix will hold the remaining 20% equity interest. Washington Prime Group ($WPG) announced that it and certain of its subsidiaries have filed voluntary petitions for relief under Chapter 11 of the United States Bankruptcy Code Healthcare Novavax ($NVAX) rises after reporting ate-stage trial data showing its COVID-19 vaccine candidate is more than 90% effective against a variety of variants of the virus as the study puts NVAX on track for filing for U.S. emergency authorization. Novavax on Friday said its vaccine candidate, NVX-CoV2373, showed immune response and protection against the highly contagious coronavirus variant originally identified in South Africa Crispr Therapeutics ($CRSP) upgraded to Neutral from Sell with a price target of $132 up from $55 at Citigroup Cano Health ($CANO) has acquired University Health Care and its affiliates for $600M, with $540M in cash and $60M in equity. Entasis Therapeutics ($ETTX) revealed in an SEC filing its biggest shareholder Innoviva Inc. ($INVA) acquired ~6.27 mln shares at an avg price of $2 per share for total amount of ~$12.54M Alzheimer industry talked about in Barron’s saying Eli Lilly’s ($LLY) donanemab is one contender with Biogen’s ($BIIB) recently approved drug this week. Gantenerumab, from Roche Holding ($RHHBY), is another. Biogen and Japan’s Eisai ($ESALY), have a third, known as BAN2401. The European Medicines Agency ($EMA) has detected a rare new side effect called capillary leak syndrome following the vaccination with the COVID-19 vaccine developed by AstraZeneca ($AZN), known as Vaxzevria in the region. Technology, Media & Telecom Alphabet Inc’s ($GOOGL) has unveiled an option for small businesses to upgrade their Gmail accounts for greater calendaring, video chat and email newsletter functionalities. Google Workspace Individua starts at $7.99 monthly and includes a temporary $2 discount Qualcomm ($QCOM) said it would be willing to invest in ARM Holdings if Nvidia’s ($NVDA) planned $40B acquisition of the Softbank-owned chipmaker isn’t able to be completed due to antitrust concerns. Barron’s noted the shortage of semiconductors has given investors a new appreciation of their importance. Taiwan Semiconductor Manufacturing (TSM) sits at the nexus of the global chip renaissance. TSMC shares are down 15% since mid-February but investors should avoid the temptation to buy the dip — for now.

/*============================================= = Friday, June 11, 2021 = =============================================*/ Futures Up/Down % Last Dow 75.00 0.22% 34,429 S&P 500 4.25 0.11% 4,233 Nasdaq 13.50 0.09% 13,963 Stock futures are looking higher, trying to build off yesterday’s gains as the S&P 500 Index posted its first closing high in over a month and as the Nasdaq Composite outperformed (rising over 0.75%) as the yield on the benchmark 10-year yield fell to its lowest levels since March, now down around the 1.43% level. Market fears of rising prices and inflation have deteriorated despite another spike in CPI yesterday when prices topped 5% on YoY basis, its highest levels since 2008 as investors hang on to the notion (implied by the Fed) that the price hikes are indeed transitory. Market gains were paced by strong gain in healthcare and REITs. In Asian markets, The Nikkei Index fell -9 points to 28,948, the Shanghai Index slid -21 points to 3,589, and the Hang Seng Index rose 103 points to 28,842. In Europe, the German DAX is up about 40 points to 15,610, while the FTSE 100 is higher by 45 points to 7,133. Market Closing Prices Yesterday The S&P 500 Index gained 19.63 points, or 0.47%, to 4,239.18 The Dow Jones Industrial Average rose 19.10 points, or 0.06%, to 34,466.24 The Nasdaq Composite jumped 108.58 points, or 0.78%, to 14,020.33 The Russell 2000 Index declined -15.72 points, or 0.68% to 2,311.41 Events Calendar for Today 10:00 AM EST University of Michigan Sentiment June-P 1:00 PM EST Baker Hughes Weekly rig count data Other Key Events: FBN Securities Silicon Valley Tech Tour (virtual), 6/10-6/11 Oppenheimer Virtual Software & Semiconductor Bus Tour, 6/7-6/11 Macro Up/Down Last Nymex 0.13 70.42 Brent 0.14 72.66 Gold -6.00 1,892.50 EUR/USD -0.0014 1.2156 JPY/USD 0.16 109.49 10-Year Note -0.021 1.437% World News The U.S. Senate Commerce Committee unveiled on Thursday a bipartisan surface transportation bill that would authorize $78 billion over five years, including sharply higher passenger rail funding, along with tougher auto safety requirements. Ten Senate Democrats and Republicans say they reached five-year, nearly $1 trillion infrastructure deal ‘; agreement calls for about $974 bln in infrastructure spending over five years without raising taxes. The package includes about $579 bln in new spending. UK Apr GDP beat m/m: 2.3% m/m vs 2.2% cons; 3m/3m 1.5% in-line; y/y 27.6% in-line; UK April Trade Balance smaller deficit: -£10.96b vs -£12.1b consensus; UK Apr Trade Balance non-EU smaller deficit: -£5.55b vs -£6.54b previous Sector News Breakdown Consumer Chewy ($CHWY) 1Q EPS $0.09 vs. est. ($0.03) on sales $2.14B vs. est. $2.13B; Gross margin of 27.6% expanded 420 bps YoY; net margin of 1.8% improved 480 bps YoY; Q1 adjusted EBITDA of $77.4M; Q1 active customers 19.8M, up 31.6% from last year Dave & Busters ($PLAY) Q1 EPS $0.40 vs. est. loss (-$0.19); Q1 revs $265.3M vs. est. $256.6M; Q1 comp store sales fell -35%; sees Q2 revs $335M-$350M vs. est. $287.4M Copa Holdings ($CPA) reports revenue passenger miles dropped 58% to 753.6M in May 2021 vs. May 2019; capacity down 53.4% to 970.9M available seat miles as compared to May 2019 Energy, Industrials and Materials The IEA forecasts global oil demand to recover to pre-pandemic levels late next year and urged OPEC and its allies to keep markets balanced by tapping their plentiful spare production capacity Livent ($LTHM) 13M share Secondary priced at $17.50 REV Group ($REVG)5M share Secondary priced at $15.50 Navigator Holdings ($NVGS) Q1 EPS $0.05 vs. est. $0.05; Q1 revs $85.7M vs. est. $71.29M Financials AGNC Investment ($AGNC) estimates tangible net book value per share of $16.82 as of May 31, 2021, down 6.4% from $17.96 it estimated at April 30. Agree Realty ($ADC) 4M share Spot Secondary priced at $71.50 Manning & Napier ($MN) reports preliminary AUM $22.1B as of May 31 Victory Capital Holdings, Inc. ($VCTR) reported assets under management (AUM) of $160.9 billion as of May 31, 2021 TaskUs ($TASK)2M share IPO priced at $23.00 Healthcare Vertex Pharma ($VRTX) shares declined over 10% after abandoning further development of VX-864 for alpha-1 antitrypsin deficiency saying that the treatment benefit seen in a phase 2 study is “unlikely to translate into substantial clinical benefit.” Jury selection began this week in a case considered one of the biggest and most complicated in the effort to hold corporations liable for the opioid crisis according to Barron’s. The trial, in New York, was delayed a year because of the pandemic. New York state and two of its counties, Nassau and Suffolk on Long Island, are suing a number of companies, including Johnson & Johnson (JNJ), McKesson ($MCK) and Teva Pharmaceutical ($TEVA), for monetary damages Tyme Technologies, Inc. ($TYME) completes strategic review, announces oasis breast trial with Georgetown University, and reports fiscal year 2021 financial results; review identified breast cancer as a priority indication for development, a focus on second-line pancreatic cancer, and continuation of trial in high-risk sarcomas CureVac ($CVAC) slides; The efficacy of CureVac’s Covid-19 vaccine is still hard to determine but is set to remain in focus as critical data from the phase 3 trial is expected this month, Berenberg says. Analysts at the bank say the trial’s progress seems encouraging and could facilitate a rapid regulatory discussion in the coming months. They expect the CVnCoV vaccine to be 70% to 80% effective – DJ PTC Therapeutics ($PTCT) announced interim results from the ongoing RAINBOWFISH trial that demonstrated pre-symptomatic infants with spinal muscular atrophy, or SMA Vertex Pharmaceuticals ($VRTX) and CRISPR Therapeutics ($CRSP) announce new data on 22 patients, with follow-up of at least 3 months, treated with CRISPR/Cas9-based gene-editing therapy, CTX001 Technology, Media & Telecom Nvidia ($NVDA) has agreed to acquire DeepMap, a startup committed to building high-definition maps for autonomous vehicles to navigate the world safely Didi Chuxing, China’s biggest ride-hailing firm, made public the filing for its long-anticipated U.S. stock market listing, setting the stage for what is expected to be the world’s biggest initial public offering this year. SeaChange ($SEAC) 1Q adj EPS ($0.07) vs. est. ($0.09) on revs $5.1Mm vs. est. $4.9Mm; qtr end backlog $20.1Mm

$CRSP 90P May21

3000 $CRSP May21 90.0 Puts trade $1.70 ASKSIDE ARCA 15:16:03 IV=87.2% +10.9 FLOOR - OPENING Vol=3122, OI=122

$CRSP looking big league

$CRSP getting mo

Upgrades 4/21: $BECI $BRG $CERC $CPA $CRSP $CSX $CTXS $FE $FSLR $FSS $ISRG $MAT $MS $NCLH $NFLX $PEP $PNFP $TTD $UNH

$CRSP having a good week

$PACB $CRSP $NVTA catching bids ..... $EDIT lags

Genomics getting hit hard today.... $CRSP $NVTA $PACB etc

CRSP Move from 100 unreal

$NVTA is a solid long term genomics play..... one of the leaders in the space with $CRSP $EDIT etc

a good fundaeental backdrop helps as well like CRSP sector ripping

Today there we decent flows into Gene therapy names like $EDIT $CRSP $PACB $NVTA etc ....I had the $NVTA lined up from the sell off a week ago and went for it when it triggered....so lets see how it plays out. Bigger picture, we should have some short side/Put plays tomorrow if this price action plays out as I think it will...a lot of names look weak.