$GSK

$BLU (+98.2% pre) Bellus stock surges after $GSK to acquire for ~$2B ($14.75/share In Cash) - SA https://seekingalpha.com/news/3957196-bellus-stock-surges-after-gsk-to-acquire-for-2b $AFMD (+7.3% pre) Affimed Shares Preclinical Data on AFM13's Mechanism of Action Demonstrating Its Potential to Induce Serial Killing at the American Association for Cancer Research Annual Meeting - MarketScreener http://ooc.bz/l/126266 $ALVO (+5.8% pre) Alvotech Says Reponses to FDA on Reykjavik Facility Deficiencies Under Review - MarketScreener http://ooc.bz/l/126268 $ATXI (+8.7% pre) Avenue Therapeutics Shares Jump on FDA Meeting Minutes - DJ http://ooc.bz/l/126269 $CVS (+1.2% pre) CVS Health names Brian Kane President of Aetna http://ooc.bz/l/126270 $EVAX (-8.6% pre) Evaxion Biotech (EVAX) Reports EVX-02 Met Primary and Secondary Endpoints in Phase 1/2a - SI http://ooc.bz/l/126272 $GMDA (+41.1% pre) Gamida Cell Shares Up 34% on FDA Approval of Omisirge Cell Therapy for Blood Cancer - MW http://ooc.bz/l/126273 $INVA (+8.4% pre) Innoviva (INVA) Announces Sulbactam-Durlobactam Unanimously Recommended for Approval by FDA Advisory Committee - SI http://ooc.bz/l/126275 $SABS (+13.0% pre) SAB Biotherapeutics Secures FDA Breakthrough Therapy Tag For Its Influenza Immunotherapy - BZ http://ooc..bz/l/126277

$GSK Feb 38 C $F Jun 17 C $PINS Jan 30 C $ERIC Jan 7 C $DUK Jan 105 C $UBS Feb 17.5 P $BABA Dec30 85/77 P $FORG Apr 20 P $U Dec30 25 P $VIX Feb 21 P $AA Jul 30 P

RECAP 12/12 Unusual Calls: $GSK Feb 38 C $F Jun 17 C $PINS Jan 30 C $ERIC Jan 7 C $DUK Jan 105 C RECAP 12/12 Unusual Puts: $UBS Feb 17.5 P $BABA Dec30 85/77 P $FORG Apr 20 P $U Dec30 25 P $VIX Feb 21 P $AA Jul 30 P

14400 $GSK FEB2023 $38 Cs trade 1.3

14400 $GSK FEB2023 $38 Cs trade 1.3

$MULN Oct28 5 C $LVS Nov25 26 P $CHPT Nov11 13/13.5 C Spd $SNAP Oct28 8 C $GSK Dec 33 C $SNAP Jan 10/16 C Spd $CHPT Nov 14 C $GM Mar 50 C

RECAP 10/24 Unusual Calls: $MULN Oct28 5 C $LVS Nov25 26 P $CHPT Nov11 13/13.5 C Spd $SNAP Oct28 8 C $GSK Dec 33 C $SNAP Jan 10/16 C Spd $CHPT Nov 14 C $GM Mar 50 C

$RIVN Sep23 35 P $EWH Dec 18 P $CCJ Nov 23 P $STWD Dec 21 P $BHC Jan-25 3 P $MSFT Oct 220 P $GSK Oct28 29 P $AAL Jan-25 5 P $WBD Oct28 9.5 P $SNAP Mar 10 P $AA Nov 25 P $MSFT Dec 210 P $SNAP Oct14 10.5 P

$RIVN Sep23 35 P $EWH Dec 18 P $CCJ Nov 23 P $STWD Dec 21 P $BHC Jan-25 3 P $MSFT Oct 220 P $GSK Oct28 29 P $AAL Jan-25 5 P $WBD Oct28 9.5 P $SNAP Mar 10 P $AA Nov 25 P $MSFT Dec 210 P $SNAP Oct14 10.5 P

2000 $GSK AUG2022 $47 Cs trade 1.4

Increasing unusual call volume: $MULN $WEAT $FHN $RSX $SLCA $FL Increasing unusual put volume: $BKR $AER $APPH $RSX $IRNT $GSK

$UL was oversold on their bid to buy part of $GSK business, since the bid was turned down and the investor reaction was so negative felt it was worth an entry

$GSK high kite

$UL down 10% on failed bid for $GSK consumer products business. Interested it is down that much even though the deal was rejected. Investors must have lost faith in managements focus and figures they might try something else would hurt share price

Upgrades 11/5: $APO $BIGC $BLDR $CLR $CWEN $EOG $GSK $IGMS $KEP $LITE $LSPD $LUMN $NFLX $NS $QCOM $QLYS $SHAK $SKT $SRPT $SYNA $SYNH $TBPH $VG

my $GSK calls working out nicely

i thought this was the gerber etf at first lol > @dros said: 3720 $GSK DEC2021 $42 Cs trade 1.00

taking a few > @dros said: 3720 $GSK DEC2021 $42 Cs trade 1.00

3720 $GSK DEC2021 $42 Cs trade 1.00

3720 $GSK DEC2021 $42 Cs trade 1.00

Tuesday, October 12, 2021 U.S. equity futures are looking mixed to slightly higher despite the cautious tone heading into the start of the third quarter earnings season with a focus on surging energy prices, faster inflation and their combined effect on growth prospects in the world’s biggest economies. Stock markets slumped in the final hour of the trading day Monday, with major averages finishing at the session lows as the Dow fell 0.72%, the S&P 500 was down 0.69%, and the Nasdaq moved down 0.64%. Overnight, Asian markets fell amid news that indebted China property giant Evergrande had missed a third coupon payment in as many weeks, reigniting concerns that its collapse could trigger contagion in regional bond markets. Bond markets reopen after being closed for the Columbus Day holiday, with the 10-year yield holding around the 1.6% level. Oil prices are trading near seven-year highs amid a global power crunch. In Asian markets, The Nikkei Index dropped -267 points to 28.230, the Shanghai Index fell -45 points to 3,546, and the Hang Seng Index declined -362 points (1.43%) to 24,962. China Evergrande Group once again misses payment on the firm’s 9.5% note due 2022 and its 10% bond due 2023. Also adding to concerns, Shanghai-based developer Sinic Holdings Group said that it doesn’t expect to pay the principal or interest due Oct 18 for a $250 mln bond not helping Asian sentiment. In Europe, the German DAX is lower by about -40 points to 15,155, while the FTSE 100 slips -30 points to 7,115. Market Closing Prices Yesterday · The S&P 500 Index dropped -30.15 points, or 0.69%, to 4,361.19 · The Dow Jones Industrial Average fell -250.19 points, or 0.72%, to 34,496.06 · The Nasdaq Composite slumped -93.34 points, or 0.64%, to 14,486.20 · The Russell 2000 Index declined -12.45 points, or 0.56% to 2,220.64 Events Calendar for Today · 6:00 AM ET NFIB Small Business Optimism · 7:45 AM ET ICSC Weekly Retail Sales · 8:55 AM ET Johnson/Redbook Weekly Sales · 10:00 AM ET JOLTs Job Openings for Aug · 4:30 PM ET API Weekly Inventory Data Earnings Calendar: · Earnings Before the Open: None · Earnings After the Close: VOXX Other Key Events: · American Society of Retina Specialists Annual Scientific Meeting, in San Antonio, TX 10/8-10/12 World News · German ZEW said economic sentiment missed: 22.3 vs 24.0 consensus; current conditions missed: 21.6 vs 28.5 consensus; the economic situation has worsened, economic o/l for next 6 months has got considerably worse · The NFIB Small Business Optimism Index: 99.1 vs. 99.5 consensus, 100.1 in August. · China’s widening power crisis, which has forced rationing across the country and threatens to derail economic growth, is prompting policy makers to rethink the pace of the nation’s energy transition – Bloomberg Sector News Breakdown Consumer · Tesla (TSLA) sold 56,006 China-made vehicles in September, up 26.5% M/M from August’s sales of 44,264 units, and the highest since it started production in Shanghai about two years ago, Reuters reports. · Automobile sales in China declined 19.6% Y/Y in September to 2.07M vehicles, falling for a fifth consecutive month; sales of passenger cars in September fell 17% Y/Y to 1.58M vehicles, the China Passenger Car Association said · MGM Resorts ($MGM) upgraded to Outperform from Neutral at Credit Suisse and up tgt to $68 from $33 · Trex Company ($TREX) downgraded to Neutral from Outperform at Baird and cut tgt to $108 from $116 saying decking channel checks suggest sell-through demand will be slower in Q3 and Q4 · Vroom ($VRM) has agreed to acquire California based United Auto Credit Corporation for $300M in cash Energy, Industrials and Materials · Matson ($MATX) guides Q3 diluted EPS $6.39-$6.58 above est. $4.39 saying they continued to see strong demand with higher year-over-year volumes compared to the largely pandemic-reduced volumes in the third quarter of last year; expects Q3 operating income for Ocean Transportation of $358M-$363M and Logistics operating income of $15M-$16M · TechnipFMC ($FTI) awarded a substantial long-term charter and services contract by Petrobras (PBR) for the pipelay support vessel Coral do Atlântico; said contract is between $250M-$500M · AO Smith ($AOS) raises quarterly dividend to $0.28 from $0.26 · AZZ Inc. ($AZZ) Q2 adj EPS $0.76 vs. est. $0.62; Q2 revs $216.45M vs. est. $219.95M; raises FY22 EPS view to $2.90-$3.20 from $2.65-$3.05 (est. $3.03); revises FY22 revenue view to $865M-$925M from $855M-$935M (est. $924.2M) · Hecla Mining ($HL) announced preliminary production results for the third quarter. Highlights include: Silver production of 2.7M ounces, decreased due to lower grades at Greens Creek based on mine sequencing, partially offset by Lucky Friday production. Gold production of 42,206 ounces, in line with the same period in the prior year Financials · China Evergrande Group once again misses payment on the firm’s 9.5% note due 2022 and its 10% bond due 2023. Also adding to concerns, Shanghai-based developer Sinic Holdings Group said that it doesn’t expect to pay the principal or interest due Oct 18 for a $250 mln bond. · Square ($SQ) upgraded to Overweight from Neutral with a $300 price target at Atlantic Equities · Arch Capital Group Ltd. ($ACGL) said Q3 results will be negatively impacted by the effects of Hurricane Ida and the July flooding events in Central Europe, as well as from other minor global events; sees pre-tax catastrophe losses of $330M-$345M in Q3 across its property casualty insurance and reinsurance segments, net of reinsurance recoveries and reinstatement premiums; board boosts share buyback program to $1.5b total · Artisan Partners Asset Management Inc. ($APAM) prelim assets under management as of September 30, 2021 totaled $173.6 billion. Artisan Funds and Artisan Global Funds accounted for $85.4 billion of total firm AUM, while separate accounts and other AUM accounted for $88.2B · Cohen & Steers, Inc. ($CNS) preliminary assets under management of $97.3 billion as of September 30, 2021, a decrease of $3.2 billion from assets under management at August 31, 2021. The decrease was due to market depreciation of $3.9 billion and distributions of $306 million, partially offset by net inflows of $1.1 billion. · Franklin Resources, Inc. ($BEN) preliminary month-end assets under management of $1,530.1 billion at September 30, 2021, compared to $1,572.1 billion at August 31, 2021. This month’s decrease in AUM primarily reflected market depreciation and slight long-term net outflows, excluding a $2 billion fixed income institutional redemption that had minimal impact on revenue. · Invesco Ltd. ($IVZ) preliminary month-end assets under management of $1,528.6B, a decrease of 2.2% versus previous month-end. Total net inflows were $4.2B. The firm achieved net long-term inflows of $3.2 billion this month. Money market net inflows were $1.0 billion. AUM was negatively impacted by unfavorable market returns, which decreased AUM by $36 billion. · Virtus Investment Partners, Inc. ($VRTS) preliminary assets under management (AUM) as of September 30, 2021 of $177.3 billion. The decrease in AUM from June 30, 2021 reflected market performance and open-end fund net outflows, partially offset by positive net flows in retail separate accounts, exchange traded funds, and institutional. Healthcare · GlaxoSmithKline’s ($GSK) consumer healthcare unit is drawing buyout interest from private equity firms such as Advent, CVC and KKR, ahead of the drugmaker’s planned separation from the unit next year, Bloomberg News reported, citing sources Technology, Media & Telecom · GitLab Inc. ($GTLB) has raised the expected pricing range of its IPO to between $66-$69 a share from between $55-$60 a share last week. The all-remote software company is still offering 8.42 million shares in the IPO, with the new pricing expectation boosting what the company will raise to $580.98 million · Relay Therapeutics ($RLAY) announces $350M common stock offering · Quanterix ($QTRX) announces that its Simoa phospho-Tau 181 (pTau-181) blood test has been granted Breakthrough Device designation by the U.S. FDA as an aid in diagnostic evaluation of Alzheimer’s Disease (AD). · SeaSpine Holdings Corporation ($SPNE) announced the full commercial launch of its NorthStar OCT Posterior Cervical Fixation System

Wednesday, August 18, 2021 Futures Up/Down % Last Dow -64.00 0.18% 35,195 S&P 500 -2.25 0.06% 4,441 Nasdaq 18.50 0.12% 15,015 U.S. futures are looking mixed ahead of the Fed Minutes, with the Dow and S&P slipping, while the tech heavy Nasdaq Corp looks to rebound after underperformance on Tuesday, as major averages fell by the most in four-weeks. Fed Minutes from the prior FOMC meeting (after 2:00 PM today) may show discussions about tapering monthly bond purchases, or just how divided FOMC officials are on the debate. Yesterday, Fed Chair Jerome Powell said the pandemic is “still casting a shadow on economic activity.” Overnight, Minneapolis Federal Reserve President Neel Kashkari said Tuesday that incoming economic data will drive the central bank’s decision on when to taper its asset purchases, noting that it’s “reasonable” to foresee such a move taking place late this year or early next year. Yesterday, the Nasdaq fell -0.9%, Dow -0.8% and S&P 500 -0.7% ended down on a day that started with pressure from Chinese equities and saw mega caps slide and home improvement names sell off after Home Depot Q2 comp sales mix. Today, rival Lowe’s (LOW) reports a beat across the board while retail giant Target (TGT) beats on the top and bottom line with slightly better comps, though shares slip. The S&P closed above Monday’s intraday low of 4,437 and today’s intraday low successfully tested a support level of 4,423, the prior high. The move comes one day after the S&P 500 had posted a 100% rise off its March 2020 closing low. It has now been 328 calendar days since the benchmark index last ended a decline of more than 5% from a record high. The current 328 calendar-day run since then end of a decline of more than 5% from a record high, is the longest such streak since early 2018. In Asian markets, The Nikkei Index rebounded, rising 161 points to 27,585, the Shanghai Index gained 38 points to 3,485, and the Hang Seng Index climbed 121 points to 25,867. In Europe, the German DAX is down -15 points to 15,900, while the FTSE 100 slides over -20 points to 7,155. Market Closing Prices Yesterday The S&P 500 Index dropped -31.63 points, or 0.71%, to 4,448.08 The Dow Jones Industrial Average fell -282.12 points, or 0.79%, to 35,343.28 The Nasdaq Composite declined -137.58 points, or 0.93%, to 14,656.18 The Russell 2000 Index declined -26.24 points, or 1.19% to 2,177.17 Events Calendar for Today 7:00 AM ET MBA Mortgage Applications Data 8:30 AM ET Housing Starts MoM for July 8:30 AM ET Building Permits MoM for July 10:30 AM ET Weekly DOE Inventory Data Earnings Calendar: Earnings Before the Open: ADI, EAT, HOOD, LITE, LOW, OSIS, PLCE, SMED, TGT, TJX Earnings After the Close: BBWI, CSCO, JBSS, KEYS, NVDA, RRGB, SNPS, SPTN, VSCO Other Key Events: EnerCom Oil & Gas Conference (virtual), 8/15-8/18 Davidson West Coast Bank Tour (virtual), 8/17-8/18 Deutsche bank Transportation Conference (virtual), 8/17-8/18 B Riley Summer Summit, 8/18-8/19 Citigroup Midstream and Energy Infrastructure Conference (virtual), 8/18-8/19 Jefferies Back-to-School Bus Tour, 8/18-8/19 Macro Up/Down Last Nymex 0.57 67.16 Brent 0.70 69.73 Gold 1.70 1,787.90 EUR/USD 0.0007 1.1717 JPY/USD 0.09 109.69 10-Year Note +0.009 1.267% Sector News Breakdown Consumer Target Corp. ($TGT) Q2 EPS $3.64 vs. est. $3.49; Q2 revs $25.16B vs. est. $25.08B; Q2 comp store sales rise +8.9% vs. est. +8.2%; q2 digital comp sales grew 10%; board approved a new, $15B share repurchase program; for 2H2 2021, expects high single digit growth in comp sales, near high end of previous guidance range; now expects FY operating income margin rate will be 8% or higher Lowe’s ($LOW) Q2 EPS $4.25 vs. est. $4.00; Q2 revs $27.6B vs. est. $26.79B; Q2 consolidated comparable sales decreased (-1.6%) vs. est. decline (-2.2%) and U.S. comparable sales decreased (-2.2%) vs. est. (-2.6%); sees FY21 revenue $92B vs. est. $91.53B; sees FY21 comp sales up 30%; sees FY21 capital expenditures $2B; Q2 cost of sales increased 1.4% to $18.26 billion, to bring gross margin down to 33.78% from 34.08% Krispy Kreme ($DNUT) Q2 EPS $0.13 vs. est. $0.14; Q2 revs $349.2M vs. est. $333.36M; qtrly net revenue growth of 43% and organic growth of 23%, up from a 6.7% decline in Q2 of 2020; sees FY organic revenue growth of 10% to 12% and sees FY adjusted Ebitda of $178M-$185M; sees FY21 revenue $1.34B-$1.38B vs. est. $1.34B Jack Henry ($JKHY) 4Q EPS $1.04 vs est. $0.93 on revs $450.3Mm vs est. $445Mm; guides FY22 adj revs $1.866-1.875B vs est. $1.882B, sees FY EPS $4.53-4.60 vs est. $4.52 La-Z-Boy ($LZB) 1Q adj EPS $0.55 vs est. $0.56 on sales $534.8Mm vs est. $485.9Mm, qtrly written comps in company-owned retail segment +22%; adj consolidated op mgn 6.6%; says rapidly escalating commodity and freight costs have not shown signs of abating, did take additional pricing actions during the qtr and imposed a surcharge on pending dealer orders in backlog; says expect margin performance to begin to improve in 2Q and see finishing FY with consolidated adj op mgn at or near dbl-digits America’s Car-Mart ($CART) Q2 EPS $3.57 vs. est. $3.49; Q2 Same store revenue growth 46.7 % and net charge-offs as a percent of average finance receivables 4.3%. Energy, Industrials and Materials The American Petroleum Institute (API) reported that crude inventories fell 1.163M barrels last week and gasoline inventories fell 1.979M barrels Copper prices eased to their lowest in a month after recent weak economic data reinforced demand fears while a looming central bankers conference focuses attention on interest rates; three-month copper on the London Metal Exchange (LME) fell for a third day JinkoSolar Holding ($JKS) supply pact with Wacker Chemie as it will supply JinkoSolar holding unit Jinko solar co. with over 70,000 tons of polysilicon from sept. 2021 to Dec. 2026 Healthcare Agilent Technologies ($A) Q3 EPS $1.10 vs. est. $0.99; Q3 revs $1.59B vs. est. $1.54B; sees Q4 EPS $1.15-$1.18 above est. $1.11; sees Q4 revenue $1.63B-$1.66B above est. $1.61B; raises FY EPS view to $4.28-$4.31 from prior $4.09-$4.14 and ups rev view GlaxoSmithKline ($GSK) receives FDA accelerated approval for Jemperli (dostarlimab-gxly) for adult patients with mismatch repair-deficient (DMMR) recurrent or advanced solid tumors Marinus Pharmaceuticals (MRNS) reports topline Ganaxolone phase 2 open-label results in tuberous sclerosis complex and receives FDA Orphan Drug designation Tilray ($TLRY) announced the acquisition of a majority of outstanding convertible notes of MedMen Enterprises ($MMNFF) held by certain funds Alcon ($ALC) Q2 core EPS $0.56 vs. est. $0.45; Q2 revs $2.1B vs. est. $1.96B; raises FY21 core EPS view to $2.00-$2.10 from $1.85-$1.95 (est. $1.93) and raises FY21 revenue view to $8B-$8.2B from $7.8B-$8B (est. $7.92B) AnaptysBio ($ANAB) announced that the U.S. FDA approved a second indication for GSK’s ($GSK) JEMPERLI for the treatment of adult patients with mismatch repair deficient recurrent or advanced solid tumors Technology, Media & Telecom CDK Global ($CDK) 4Q adj EPS $0.66 vs est. $0.67 on revs $420.1Mm vs est. $427.7Mm; guides FY22 adj EPS $2.70-2.90 vs est. $3.02, sees FY revs $1.78-1.82B vs est. $1.78B Cree Inc. ($CREE) shares fell -4%; 4Q adj EPS ($0.23) vs est. ($0.24) on revs $145.8Mm vs est. $145.2Mm; guides 1Q adj EPS loss $0.21-0.25 vs est. loss $0.23, sees 1Q revs $144-154Mm vs est. $153.4Mm Cree ($CREE) and STMicroelectronics (STM) announced the expansion of an existing multi-year, long-term silicon carbide wafer supply agreement Instructure Holdings (INST) 2Q ($0.17) on revs $93.6Mm; guides 3Q revs $100.4-101.4Mm, sees 3Q adj net income $21.2-22.2Mm; guides FY adj net income $87.2-89.2Mm Weibo ($WB) Q2 EPS $0.79 vs. est. $0.63; Q2 revs $574.47M vs. est. $527.89M; Q2 monthly active users were 566M in June, a net addition of 43M users on a YoY basis; Q2 mobile MAUs represented 94% of MAUs. Average daily active users were 246M in June, a net addition of 16M users yoy; sees Q3 revs up 20%-25% ViacomCBS ($VIAC) upgraded to Overweight from Equal Weight at Wells Fargo with a price target of $60, up from $45 saying the company’s streaming efforts are bearing fruit and have impressed us, so is moving from historical bears to constructive bulls Bottomline Technologies ($EPAY) announces up to $50M stock repurchase plan

986 $GSK FEB2022 $39 Cs trade 1.8

986 $GSK FEB2022 $39 Cs trade 1.8

RECAP 6/25 Chatter: $IRWD + Setting up for sale (Dealreporter) $KNDI + Tweets Kandi America is ready $FSR + Henrik Fisker Tweet $GSK + Hires GS & C to spinn off consumer health biz

Wednesday, June 23, 2021 Futures Up/Down % Last Dow 50.00 0.15% 33,885 S&P 500 2.50 0.06% 4,239 Nasdaq 14.75 0.10% 14,273 Markets are looking modestly higher in the U.S., tracking gains in Europe and Asia as investors appear at ease over the inflation picture after Federal Reserve Chairman Powell reiterated yesterday in testimony to Congress that a spike in inflation likely was temporary, easing worries that the central bank could pull back on economic support. Stocks closed higher on Tuesday as the Nasdaq posted a record closing high, boosted by shares of large cap tech as Amazon, Microsoft, and Apple paced the gains in a further rotation into growth stocks. Amazon produced over $5.6 billion in total online sales in the United States on the first day of its Prime promotional event, according to Adobe Digital Economy Index. Helping boost markets further, Federal Reserve Chair Jerome Powell reaffirmed the U.S. central bank’s view during his testimony to Congress on the U.S. economy to not to raise interest rates too quickly based on the fear of coming inflation. Most of the 11 major S&P sector indexes rose, with consumer discretionary and energy among the biggest gainers, erasing most of last week’s market declines. In Asian markets, The Nikkei Index slipped -9 points to 28,874, the Shanghai Index rose 8 points to 3,566, and the Hang Seng Index jumped 507 points to 28,817. In Europe, the German DAX is down -75 points to 15,560, while the FTSE 100 is up 20 points to 7,110. Oil rises back above $75 as API weekly data shows stockpiles drop/shows tight market; Bitcoin rebounds 7% to $34,000, a more than $5,000 move off yesterday lows, having plunged more than 50% from its all-time highs above $65,000 in mid-April; Treasury yields remains little changed/tight range as 10-year at 1.475%. Market Closing Prices Yesterday The S&P 500 Index gained 21.65 points, or 0.51%, to 4,246.44 The Dow Jones Industrial Average rose 68.61 points, or 0.20%, to 33,945.58 The Nasdaq Composite jumped 111.79 points, or 0.79%, to 14,253.27 The Russell 2000 Index advanced 111.79 points, or 0.43% to 2,295.95 Events Calendar for Today 7:00 AM ET MBA Mortgage Applications Data 9:45 AM ET Markit Composite flash PMI, June 9:45 AM ET Markit Manufacturing Services PMI, June…est. 61.5 10:00 AM ET New Home Sales MoM for May…est. 870K 10:30 AM ET Weekly DOE Inventory Data Earnings Calendar: Earnings Before the Open: $PDCO, $WGO Earnings After the Close: $CNXC, $FUL, $KBH, $SCS Other Key Events: BMO Capital 2021 Chemical & Packaging Conference (virtual), 6/23 Goldman Sachs 17th Business Services, Transport & Leisure Conference (virtual), 6/21-6/23 Raymond James Human Health Innovation Conference (virtual), 6/21-6/23 Roth London Conference (virtual), 6/21-6/23 Jefferies Consumer Conference (virtual), 6/22-6/23 JPMorgan 2021 Energy, Power & Renewables Conference (virtual), 6/22-6/23 JPMorgan Payment & FinTech Forum (virtual), 6/23-6/24 Sidoti Investor Conference (virtual), 6/23-6/24 Macro Up/Down Last Nymex 0.45 73.30 Brent 0.55 75.36 Gold 4.30 1,783.005 EUR/USD 0.0006 1.1946 JPY/USD 0.34 110.99 10-Year Note +0.003 1.475% Sector News Breakdown Consumer Xpeng ($XPEV) shares rise upon on receiving approval to list on Hong Kong stock exchange; the company could raise as much as $2B in Hong Kong as soon as this year Energy, Industrials and Materials The American Petroleum Institute ($API) showed a draw of 7.2M barrels of oil in the latest week, gasoline inventories show a build of 959K barrels, distillate inventories show a build of 992K barrels and Cushing inventories show a draw of 2.55M barrels. Clean Energy Fuels ($CLNE) said it contributed $50M to its 50-50 joint venture with BP Plc ($BP) and forced the conversion of BP’s Class B units into Class A units. Parker-Hannifin (PH) upgraded to Overweight from Sector Weight at KeyBanc United Rentals ($URI) upgraded to Buy from Neutral at Citi Financials IHS Markit ($INFO) Q2 adj EPS 81c vs. est. 80c; Q2 revs $1.18B vs. est. $1.13B; raises FY21 adjusted EPS view to $3.15-$3.17 from $3.11-$3.16 (est. $3.16), ups FY21 revenue view to $4.635B-$4.675B from $4.535B-$4.635B (est. $4.6B) and boosts FY21 adj EBITDA view to $2.02B-$2.03B from $2B-$2.03B Global Self Storage ($SELF)12M share Spot Secondary priced at $5.35 Intercontinental Exchange ($ICE) upgraded to Conviction Buy from Buy at Goldman Sachs LPL Financial ($LPLA) downgraded to Buy from Conviction Buy at Goldman Sachs Healthcare BioXcel Therapeutics Inc ($BTAI) launches $100M stock offering with $15M overallotment option on behalf of related stockholder Enanta Pharmaceuticals ($ENTA) says announced positive data from the first two dose cohorts of its Phase 1b study of EDP-514 in viremic chronic HBV patients who were not being treated with a nucleoside reverse transcriptase inhibitor Gemini Therapeutics ($GMTX) announces initial data from its ongoing phase 2a study of gem103 in patients with geographic atrophy secondary to dry age-related macular degeneration GlaxoSmithKline PLC ($GSK) said that it expects growth in sales and adjusted operating profit over the next five years to be underpinned by new vaccines and specialty medicines, as it set targets for the medium and l-t following planned 2022 demerger of its consumer healthcare business. Hologic ($HOLX) has received CE mark for its new Aptima CMV Quant assay in Europe, the company announced United Therapeutics Corp. ($UTHR) and Medtronic Inc. ($MDT) have agreed to stop further efforts to develop and commercialize the implantable system for Remodulin, or ISR; the companies plan to wind down the development program and to support patients already enrolled in clinical studies of the ISR at United Therapeutics’ sole expense Second Sight ($EYES) 10M share Spot Secondary priced at $5.00 Teva Pharmaceuticals ($TEVA) announced its U.S. launch of the first generic version of twice daily PERFOROMIST, formoterol fumarate inhalation solution, 20 mcg/2 ML, indicated to treat bronchoconstriction in patients with chronic obstructive pulmonary disease, including chronic bronchitis and emphysema Technology, Media & Telecom Intel Corp. ($INTC) said it would create two new business units that would focus separately on software and high-performance computing and graphics; also said current executives Sandra Rivera and Raja Koduri will take on new senior leadership roles, while technology industry veterans Nick McKeown and Greg Lavender will join Intel. Corning ($GLW) said midday yesterday it is increasing its display glass substrate prices for Q3 “moderately” due to higher logistics and materials costs and other operational expenses during the extended glass shortage Bentley Systems ($BSY) announces offering of $500M of convertible senior notes Sprinklr ($CXM)625M share IPO priced at $16.00

Upside: -ENOB +159% (announces FDA Acceptance of Pre-IND Request for Potential HIV Cure) -ITOS +51% (GSK and iTeos announce development and commercialisation collaboration for EOS-448) -CRSR +15% (hearing interest from WallStreetBets) -NVAX +9.0% (COVID-19 vaccine demonstrates 90% overall efficacy and 100% protection against moderate and severe disease in PREVENT-19 Phase 3 trial) -LPCN +8.3% (FDA clears LPCN 1154 IND application for a Phase 2 Postpartum Depression Study) -RIOT +8.3% (crypto strength following TSLA CEO Musk indicating car maker may resume BTC transactions) -HAPP +7.8% (signed agreement to distribute Volkswagen Electric Vehicles) -MARA +7.8% (crypto strength following TSLA CEO Musk indicating car maker may resume BTC transactions) -RAPT +7.7% (reports positive topline results from Phase 1b Trial of RPT193 Monotherapy in Atopic Dermatitis) -AMTX +6.0% (signs $200M biofuels offtake agreement with international renewable fuels supplier Murex, LLC to be delivered during 2021 to 2023) -OCC +5.4% (earnings) -EFOI +4.8% (enters marketing partnership with FirstEnergy Home and FirstEnergy Advisors) -TWST +3.2% (collaborates with Regeneron for production of genotyping by sequencing panel to enable diverse genome-wide screening) -HGEN +2.8% (initiates Submission for Lenzilumab Marketing Authorization in COVID-19, to the United Kingdom’s Medicines and Healthcare Products Regulatory Agency (MHRA)) -CODA +2.3% (earnings) -OTLK +2.3% (announces inclusion in the Russell 2000 Index, effective June 25, 2021) -SVOK +1.1% (confirms Boxed to go public through merger with Seven Oaks Acquisition Corp. in deal valued at ~$900M) Downside: -ATXI -47% (receives Complete Response Letter from the FDA for IV Tramadol, saying it does not support benefits as a monotherapy) -RIDE -11% (CEO and CFO resign following results of special committee investigation of Hindenburg Research report) -HEXO -3.6% (earnings) -NKLA -1.5% (discloses entered into a purchase agreement and a registration rights agreement with Tumim Stone Capital to sell $300M of the Nikola's common stock)

/*============================================= = MORNING UPDATE - Thursday 05/27/21 = =============================================*/ Futures Up/Down % Last Dow -9.00 0.03% 34,271 S&P 500 -8.25 0.20% 4,184 Nasdaq -54.50 0.40% 13,646 Stock futures are edging slightly lower ahead of a busy morning of economic data, as investors await monthly GDP (2nd estimate for Q1 with estimate about 6.4% – in-line with prior reading), jobless claims data, durable goods and pending home sales. The narrative remains the same day after day as the U.S. economy continues to show improvement/rebound from pandemic lows, which has raised concerns over rising inflation and fears the Fed could pull back on its asset purchases/monetary policy – but most official have said over the last week they don’t feel it will be necessary to change course since rising price pressures likely will just be transitory. Market fears remain non-existent again as the CBOE Volatility Index (VIX) comes into the day below the 18 level (was above 27 just over a week ago). In Asian markets, The Nikkei Index fell -93 points to 28,549, the Shanghai Index rose 15 points to 3,608 and the Hang Seng Index fell -52 points to 29,113. In Europe, the German DAX is down over 40 points to 15,400, while the FTSE 100 is down a few points to 7,015. Stocks edged higher on Wednesday, with the SmallCap Russell 2000 index leading (up nearly 2%), and the tech heavy Nasdaq Composite, as markets were once again spurred by further reassuring talk from Federal Reserve officials that spiking inflation will be “transitory” with Treasury yields remaining lower. Fed Vice Chair Randal Quarles was the latest Fed official to ease worries about inflation. Outside of SmallCap and tech, momentum related sectors fueled the rally with social media “meme” stocks surging ($GME, $AMC, $EXPR, $KOSS), along with electric vehicle names and Bitcoin leveraged stocks. Events Calendar for Today 8:30 AM EST Gross Domestic Product (GDP) Q1 (2nd) …est. 6.5% 8:30 AM EST GDP Price Deflator Q1 (2nd) …est. 4.1% 8:30 AM EST GDP Consumer Spending for Q1 (2nd) 8:30 AM EST Core PCE Prices for Q1…est. 2.3% 8:30 AM EST PCE Prices Prelim for Q1 8:30 AM EST Weekly Jobless Claims…est. 425K 8:30 AM EST Continuing Claims…est. 3.68M 8:30 AM EST Durable Goods for April…est. 0.7% 8:30 AM EST Durable Goods Ex Transports for April…est. 0.8% 10:00 AM EST Pending Home Sales MoM for April…est. 0.8% 10:30 AM ET Weekly EIA Natural Gas Inventory Data 11:00 AM EST Kansas City Fed Manufacturing for May Earnings Calendar: Earnings Before the Open: $AMWD, $BBY, $BURL, $DG, $DLTR, $DXLG, $GCO, $HLNE, $MOV, $PLAN, $SAFM, $TITN Earnings After the Close: $ADSK, $BOX, $COST, $CRM, $DELL, $DOMO, $GPQ, $HPQ, $KRT, $LGF.A, $OLLI, $ULTA, $VEEV, $VMX, $YEXT Other Key Events: Goldman Sachs TechNet Conference Asia Pacific 2021 (virtual), 5/24-5/28 Microsoft Build Conference (virtual), 5/25-5/27 New Relic Future Stack Conference (virtual), 5/25-5/27 UBS Global Oil & Gas Conference (virtual), 5/25-5/27 Wolfe Research Transport & Industrials Conference (virtual), 5/25-5/27 Cowen Digital Dining Summit (virtual), 5/27 Market Closing Prices Yesterday The S&P 500 Index climbed 7.86 points, or 0.19%, to 4,195.99 The Dow Jones Industrial Average rose 10.59 points, or 0.03%, to 34,323.05 The Nasdaq Composite jumped 80.82 points, or 0.59%, to 13,738.00 The Russell 2000 Index surged 43.52 points, or 1.97% to 2,249.27 Macro Up/Down Last Nymex -0.48 65.73 Brent -0.50 68.37 Gold -1.00 1,895.70 EUR/USD 0.0012 1.2204 JPY/USD 0.02 109.17 10-Year Note +0.012 1.586% Sector News Breakdown Consumer American Eagle ($AEO) 1Q adj EPS $0.48 vs. est. $0.46 on revs $1.03B vs. est. $1.02B, says digital momentum continued with revs +57% (Aerie +158%, AE +20%); total inventory +2% vs 2019 Cavaco Industries ($CVCO) Q4 EPS $2.71 vs. est. $1.92; Q4 revs $306.5M vs. est. $293.79M; home sales order rates improved 50% over last year’s quarter; backlogs increased $131M during the quarter; Designer Brands ($DBI) 1Q adj EPS $0.12 vs. est. ($0.18) on sales $703.2Mm vs. est. $651Mm, comps +52.2% Elf Beauty ($ELF) Q4 adj EPS $0.71 vs. est. $0.10; Q4 sales $92.7M vs .est. $82.4M; sees 2022 adj EPS 64c-67c vs. est. 71c and sees year revs $343M-$350M vs. est. $334.3M; Q4 Selling, general and administrative expenses rose 23% to $57.9M Modine Manufacturing ($MOD) Q4 adj EPS $1.14 vs. est. $0.27; Q4 sales $514.9M vs. est. $493M; sees full-year 2022 YoY sales up 12%-18% William-Sonoma ($WSM) Q1 adj EPS $2.93 vs. est. $1.83; Q1 revs $1.75B vs. est. $1.52B; Q1 comp brand revenue growth accelerated to 40.4%, with all brands accelerating sequentially including West Elm at 50.9%, Pottery Barn at 41.3%, Williams Sonoma at 35.3% and Pottery Barn Kids and Teen at 27.6%; raising fiscal year 2021 outlook to low double-digit to mid-teen net revenue growth; for long-term, planning for net rev growth of mid-to-high single digits & non-Gaap operating margin expansion Azek ($AZEK) 15M share Secondary priced at $43.50 Crocs Inc. ($CROX) will replace Cantel Medical Corp. ($CMD) in the S&P MidCap 400, and Organogenesis Holdings Inc. ($ORGO) will take Crocs’ spot in the S&P SmallCap 600 before trading opens on June 2, according to S&P Dow Jones Indices. Energy, Industrials and Materials Vertex Energy ($VTNR) surged after hours after agreeing to acquire the Mobile refinery in Alabama from Royal Dutch Shell (RDS.A) for $75M Ranpak Holdings ($PACK) 5M share Spot Secondary priced at $21.00 The Department of Homeland Security issued a new security directive for pipeline owners and operators on Thursday after a hack of the Colonial Pipeline disrupted fuel supplies in the southeastern United States for days this month Healthcare Change Healthcare ($CHNG) 4Q adj EPS $0.42 vs. est. $0.36 on revs $855.2Mm vs. est. $840.2Mm; says due to recently announced transaction with Optuminsight, will no longer by providing guidance Ironwood Pharmaceuticals ($IRWD) announces agreement with Teva (TEVA) involving Linzess® (linaclotide) 72 mcg dosage strength Myovant Sciences ($MYOV) and Pfizer ($PFE) receive FDA approval for Myfembree®, the first once-daily treatment for heavy menstrual bleeding associated with uterine fibroids Nextgen Healthcare ($NXGN) Q4 adj EPS 21c vs. est. 19c; Q4 revs $144.2M vs. est. $140.1M; sees FY22 adj EPS 89c-95c vs. est. 99c; sees FY22 revs $574M-$584M vs. est. $577.2M; Subscription services revenue in Q4 generated $38.2M, or 16% growth over the prior year period, driven by demand for patient experience-related solutions. Day One ($DAWN) 10M share IPO priced at $16.00 Oak Street Health ($OSH)05M share secondary priced at $62.00 Ocugen ($OCGN) says it is on track to submit emergency use authorization application (EUA) to U.S. FDA for its COVID-19 vaccine, Covaxin, in June; awaiting feedback from FDA after master file regarding vaccine was submitted in March R1 RCM ($RCM) 15M share secondary priced at $22.50 Singular Genomics Systems ($OMIC)2M share IPO priced at $22.00 VIR Biotech ($VIR) received FDA emergency use approval for its antibody treatment co-developed with Glaxo ($GSK) to treat mild-to-moderate COVID-19 in people aged 12 years and older Technology, Media & Telecom NVIDIA ($NVDA) Q1 non-Gaap EPS $3.66 vs. est. $3.28; Q1 revs $5.66B vs. est. $5.41B; qtrly data center revenue of $2.05B, up 79% from a year earlier; Q1gaming revenue of $2.76B, up 106% from a year earlier; sees Q2 revs expected to be $6.30B, plus or minus 2% vs. est. $5.5B; Q2 Gaap and non-Gaap gross margins are expected to be 64.6% and 66.5%, respectively, plus or minus 50 bps after Q1 margins 64.1% vs 65.1% YoY and Q1 non-Gaap gross margin 66.2% vs 65.8% YoY Disneyland ($DIS) to allow non-California guests starting on June 15; Disneyland extends reservation window to 120 days DXC Technology ($DXC) Q4 adj EPS 74c vs. est. 70c; Q4 revs $4.385B vs. est. $4.28B; Q4 bookings were $4.7B; sees FY22 adj EPS $3.45-$3.65 vs. est. $3.44; sees FY22 revenue $16.6B-$16.8B vs. est. $16.91B Nutanix ($NTNX) Q3 adj EPS loss (41c) vs. est. loss (49c); Q3 revs $344.5M vs. est. $334.45M; Q3 billings down 3.2% YoY to $371.1M; guides Q4 ACV billings $170M-$175M and Q4 adjusted gross margin roughly 81.5%-82% Okta Inc. ($OKTA) 1Q adj EPS ($0.10) vs. est. ($0.20) on revs $251Mm vs. est. $238.3Mm; guides 2Q adj EPS loss $0.35-0.36 vs. est. loss $0.11, sees 2Q revs $295-297Mm vs. est. $258.2Mm; guides FY adj EPS loss $1.13-1.16 vs. est. loss $0.44, sees FY revs $1.215-1.225B vs. est. $1.09B; says CFO stepping down June 1st, Brett Tighe (Treasurer) will be interim CFO Ooma Inc. ($OOMA) Q1 EPS $0.11c vs. est. $0.08; Q1 revs $45.6M vs. est. $44.31M; sees Q2 EPS 8c-10c vs. est. 6c; guides Q2 revs $46.0M-$46.8M vs. est. $45.12M; sees FY22 EPS 30c-38c vs. est. 29c; sees year revs $185M-$187M vs. est. $183.64M Pure Storage ($PSTG) Q1 adj EPS 0c vs. est. loss (6c); Q1 revs $412.7M vs. est. $403.91M; sees Q2 revs $470M vs. est. $455.85M; sees Q2 non-GAAP operating income $15M; Q1 Subscription services revenue $162.8 million, up 35% YoY; Q1 GAAP gross margin 68.3%; non-GAAP gross margin 70.5% QAD Inc. ($QADA) 1Q EPS $0.09 vs. est. $0.12 on revs $83Mm vs. est. $78.9Mm, subscription revs $36.7Mm; guides 2Q subscription revs $38.5Mm, maintenance revs $26zmm, sees 2Q op income $1Mm incl stock comp exp $5Mm; guides FY subscription revs $160Mm, maintenance revs $102Mm, op inc $12Mm incl stock comp exp $17Mm Snowflake ($SNOW) 1Q EPS ($0.70) vs. est. ($0.16) on revs $228.9Mm vs. est. $212.9Mm, qtr-end total customers were 4,532; guides 2Q product revs $235-240Mm vs. est. $251Mm; guides FY product revs $1.02-1.04B vs. est. $1.09B Workday ($WDAY) 1Q adj EPS $0.87 vs. est. $0.73 on revs $1.18B vs. est. $1.16B, qtrly subscription revs $1.03B +17%; guides 2Q subscription revs $1.095-1.097B; raises FY subscription revs guide to $4.425-$4.44B, raises FY adj op mgn guide to 18-19%; Zuora ($ZUO) 1Q adj EPS ($0.02) vs. est. ($0.04) on revs $80.3Mm vs. est. $79Mm; guides 2Q adj EPS loss $0.04-0.03 vs. est. loss $0.02, sees 2Q revs $82.5-84.5Mm vs. est. $81.8Mm; guides FY adj EPS loss $0.10-0.06 vs. est. loss $0.08, sees FY revs $337-339Mm vs. est. $336.3Mm FIGS ($FIGS)4M share IPO priced at $22.00 Thryv Holdings ($THRY)24M share Secondary priced at $23.50

European Markets Finished mostly lower yesterday, amid worries about rising inflation and concerns over surging coronavirus cases in Asia. Compagnie de Saint-Gobain dropped 1.6%, after the building materials group agreed to acquire Romanian group Duraziv, specialised in the production of adhesives and other construction chemicals solutions. Aareal Bank fell 1.1%, after the company announced leadership changes. Bayer slid 0.7%, after the company lost its second appeal of the three jury verdicts finding that its Roundup weed killer causes cancer. On the flipside, Sanofi added 1.1%, as the pharmaceutical company and Britain’s GSK reported “strong immune responses” in in early-stage clinical trial results of their coronavirus vaccine. The FTSEurofirst 300 index slightly gained, to settle at 1,704.7. The German DAX Xetra fell 0.1%, to settle at 15,396.6, while the French CAC-40 shed 0.3%, to close at 6,367.4. .

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Lo que les mencioné hace unos dias sobre GSK y Sanofi, ya estan empezando a vender su humo.

es igual que Sanofi y su alianza con GSK, dentro de poco van a avisar lo mismo que Pfizer hoy y va ser solo para levantar un poco el valor de las acciones

Pfizer se inyecto de dinero con la venta de una de sus divisiones a GSK a finales del año pasado, pero creo que tienen que levantar humo para salir un poco a flote de las deudas que cargan

And finally what's happening today - aside from the BOC - Chief Execs of Twitter, Alphabet & FB are up before the Senate for a hearing on Section 230 of the Communications Decency Act which gives tech platforms immunity from being sued over user-generated content. Should be interesting. And earning today include Boeing, UPS, Mastercard & Visa - all companies that reflect the impact of the virus (good & bad). Plus we have GSK & Gilead.

Aztra, GSK, y JNJ son empresas a tradear en un futuro próximo pero no ahora. La verdad es que la vacuna no existe y los ensayos clínicos eso han demostrado. Es por eso que el segundo cierre es mas real que una vacuna viable este año.

On a happier note – the New York Times reported that the US Centers for Disease Control and Prevention informed officials to get ready to distribute a potential coronavirus vaccine as early as October. There are several candidates are in the running and there is clearly a lot more confidence we will have a vaccine and be able to declare victory over Covid. Sanofi and GSK announced today the start of their Phase 1/2 clinical trial for their adjuvanted Covid-19 vaccine. If the trials are positive, the companies aim to move into a Phase 3 trial by end of 2020 and target producing up to one billion doses in 2021.

La sperimentazione del vaccino contro il coronavirus avviata dalle aziende farmaceutiche GSK e Sanofi

Never mind all that for now though, stocks keep going up. The S&P 500 rose 1.4 per cent to end at 3,380, just six points under its record closing high at 3,386.15, with the record intraday peak at 3,393.52. Asian stocks broadly followed through, with shares in Tokyo up almost 2 per cent. European stocks failed to take the cue and were a little soft on the open, with the FTSE 100 the laggard at -1 per cent, though 22.3pts are due to BP, Shell, Diageo, AstraZeneca, GSK and Legal & General among others going ex-dividend.

Watch: $D, $AAPL, $BABA, $LMND, $AMD, $WKHS, $NVAX, $CHGG, $GSK, $UBER, $USO-Current long swing.

En resumen, si quieren invertir en empresas de investigación es mejor ir a lo seguro, Prizer, Sanofi, GSK. Las chinas son del gobierno chino y no se que empresas esten involucradas.

que significa, la producción en masa puede verse comprometida y la gigante de su país que es GSK puede interferir en que salga a luz su vacuna o que se quede "estancada" en la investigación

Sanofi y GSK unieron fuerzas en biotecnología y por las mismas fechas esperan sacar tambien su vacuna