$PTCT

PTC Therapeutics Inc

  • NASDAQ
  • Health Technology
  • Biotechnology
  • Manufacturing
  • Pharmaceutical Preparation Manufacturing

PRICE

$30.35 -

Extented Hours

VOLUME

652,944

DAY RANGE

30.02 - 31.4

52 WEEK

29.94 - 45.8

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Friday, October 29, 2021 Futures Up/Down % Last Dow -45.00 0.13% 35,568 S&P 500 -22.25 0.49% 4,565 Nasdaq -139.50 0.88% 15,625 After trading to all-time highs Thursday for the S&P 500, Dow Jones, and Nasdaq Composite (and a 2% gain for the Russell 2000 as well) on strong earnings as well as positive developments on the spending bill in Washington, futures are pulling back. Shares of tech and retail giants Apple (AAPL) and Amazon (AMZN) are lower by 3% and 4% respectively after AAPL’s iPhone and overall revs miss for the quarter and AMZN drops on a Q3 revs miss, lower op income and lower guidance, sending Nasdaq Futures lower by about 1%. Investor sentiment is also starting to turn cautious amid the steady stream of corporate warnings on inflationary pressures and supply chain woes. Big day of inflation data with the personal spending and income for Sept and PCE inflation data expected at 8:30 AM. The 10-year Treasury yield is up around 1.61%, recovering off mid-week lows around the mid 1.5% level. Bitcoin prices are lower holding around the $60K level while oil futures are on track to snap their 8-week winning streak. In Asian markets, The Nikkei Index rises 0.25% to 28,890, the Shanghai Index gains 0.8% to 3,547, and the Hang Seng Index falls =0.7% to 25,377. In Europe, the German DAX is lower -1.2% to 15,500, while the FTSE 100 down -0.5% at 7,210. Market Closing Prices Yesterday The S&P 500 Index gained 44.74 points, or 0.98%, to 4,596.42 The Dow Jones Industrial Average rose 239.79 points, or 0.68%, to 35,730.48 The Nasdaq Composite surged 212.28 points, or 1.39%, to 15,448.12 The Russell 2000 Index advanced 45.49 points, or 2.02% to 2,297.98 Events Calendar for Today 8:30 AM ET Personal Income for September…est. (-0.2%) 8:30 AM ET Personal Spending for September…prior +0.4% 8:30 AM ET PCE Price Index MoM for September 8:30 AM ET PCE Price Index YoY for September 8:30 AM ET Core PCE Price Index MoM for September…est. +0.2% 8:30 AM ET Core PCE Price Index YoY for September…est. +3.7% 9:45 AM ET Chicago PMI for October…est. 63.5 (prior 64.7) 10:00 AM ET University of Michigan Confidence, Oct-F…est. 71.4 1:00 PM EST Baker Hughes Weekly rig count data Earnings Calendar: Earnings Before the Open: ABBV, AON, B, BAH, CERN, CHD, CHTR, CL, COWN, CVX, DCOM, HUN, IRMD, LHX, PIPR, POR, PSX, PSXP, RUTH, WY, XOM Macro Up/Down Last Nymex 0.34 83.15 Brent 0.37 84.69 Gold -2.95 1,795.95 EUR/USD -0.0029 1.1652 JPY/USD 0.19 113.76 10-Year Note +0.041 1.61% Sector News Breakdown Consumer com (AMZN) shares fall -3%; 3Q EPS $6.12 vs est. $8.92 on sales $110.8B vs est. $111.6B, AWS net sales $16.11B; guides 4Q sales $130-140B vs est. $142B; sees q4 operating income is expected to be between $0 and $3.0 bln, compared with $6.9 bln in q4 2020; in q4, expect to incur several bln dollars of additional costs in consumer business as we manage through labor supply shortages Starbucks (SBUX) Q4 EPS $1.00 vs. est. $0.99; Q4 revs rose 31% to $8.1B vs. est. $8.21B; commits to $20 bln of share repurchases and dividends over next three years; qtrly active Starbucks rewards membership in U.S. approaches 25 mln, up 28% YoY; qtrly comp store sales of 17% globally; qtrly international comp store sales grew 3%; qtrly comp store sales of 22% in U.S.; comp store sales decreased 7% in China Columbia Sportswear (COLM) 3Q EPS $1.52 vs est. $1.33 on revs $804.7Mm vs est. $862Mm; qtrly inventory -7%; guides FY net sales +21.5-23% vs prior +25-26.5% and est. +26.5%, sees FY EPS $4.55-4.80 vs est. $4.65; says believe can achieve mid-teens or better net sales growth in 2022 vs est. +10% Decker’s Outdoors (DECK) 2Q EPS $3.66 vs est. $4.00 on sales $721.9Mm vs est. $765.9Mm, comps +1%; sees FY EPS $14.15-15.15 vs est. $15.15; Gross margin was 50.9% compared to 51.2% for the same period last year; Decker’s also said: UGG(R) brand net sales for the second quarter increased 8.0% to $448.4 million compared to $415.1 million for the same period last year. HOKA(R) brand net sales for the second quarter increased 47.0% to $210.4 million compared to $143.1 million for the same period last year. Teva(R) brand net sales for the second quarter increased 4.0% to $28.8 million compared to $27.7 million for the same period last year. Frontdoor (FTDR) 3Q EPS $0.89 vs est. $0.68 on revs $471Mm vs est. $476.5Mm; guides 4Q revs $330-340Mm vs est. $347.7Mm, sees FY revs $1.59-1.6B vs est. $1.62B Mohawk Industries (MHK) Q3 adj EPS $3.95 vs. est. $3.81; Q3 revs $2.817B vs. est. $2.9B; guides Q4 EPS $2.80-$2.90 vs. est. $3.23 Skecher’s (SKX) Q3 EPS $0.66 vs. est. $0.73; Q3 sales rose 19.2% to $1.55B vs. est. $1.63B; guides Q4 EPS $0.28-$0.33 vs. est. $0.34 and year EPS view cut to $2.45-$2.50 from $2.55-$2.65; cuts FY21 revenue view to $6.15B-$6.2B from $6.15B-$6.25B; Direct-to-Consumer sales grew 44.1% and wholesale sales grew 10.5% SkyWest (SKYW) 3Q adj EPS $1.45 vs est. $0.70 on revs $745Mm vs est. $687.7Mm; says experienced a severe outage in October resulting in about 1,700 flight cancelations and expect may impact 4Q results from $15-20Mm pre-tax; Texas Roadhouse (TXRH) Q3 EPS $0.75 vs est. $0.81 on revenue $869.9M vs est. $869.4M; comp sales +30.2% vs 3Q20, +22.3% vs 2019, partially offset by higher food/beverage costs with commodity inflation 13.9% driven by higher beef prices; sees positive comp sales in FY22, commodity cost inflation in high-teens in 1H22 Energy Chevron (CVX) Q3 adj EPS $2.96 vs. est. $2.21; Q3 revs $43B vs. est. $40.52B; posted net income of $6.11B vs. a loss of $207M a year ago; said Q3 average sales price per barrel of crude oil and natural gas liquids was $58, vs $31 a year earlier Dril-Quip (DRQ) 3Q EPS ($0.31) vs est. ($0.14) on revs $83Mm vs est. $85.6Mm, sees 4Q bookings at high end of $40-60Mm range (unchanged from prior view) First Energy (FE) Q3 adj EPS $0.82 vs. est. $0.79; Q3 revs $3.1B in-line with ests; raises FY21 adj EPS view to $2.55-$2.65 from $2.40-$2.60 (est. $2.54) SM Energy (SM) Q3 EPS $0.69 vs. est. $0.13; Q3 revs $760.24M vs. est. $510.61M; Q3 Production was 14.3 MMBoe (155.8 MBoe/d) and was 56% oil; the Company is increasing guidance for 2021 production volumes to 49.5-50.0 MMBoe (135.6-137.0 MBoe/d) Financials Hartford Financial (HIG) Q3 core EPS $1.26 vs. est. $0.86; Net income ROE for the trailing 12-month period ended Sept. 30, 2021 was 12.3% and core earnings ROE* for the same period was 12.5%; the Commercial Lines combined ratio was 101.2 in third quarter 2021 with an underlying combined ratio* of 87.2, a 6.5-point improvement YoY LPL Financial (LPLA) Q3 EPS $1.77 vs est. $1.75 on revenue $2.02B vs est. $2.05B; total advisory and brokerage assets $1.13 trillion (+40% YoY), organic net new assets $27B (+10% annualized) in the qtr, $110B over past 12-months (+14% annualized) Riley Financial (RILY) announced a $4 dividend, composed of a $3 special one-time payout and a doubling of its regular quarterly dividend to $1 Healthcare 4D Molecular (FDMT)75M share Secondary priced at $25.00 AirSculpt Technologies (AIRS) 7M share IPO priced at $11.00 Aura Biosciences (AURA) 5M share IPO priced at $14.00 Entrada Therapeutics (TRDA)075M share IPO priced at $20.00 Sonendo (SONX)8M share IPO priced at $12.00 Valneva (VALN)5M share Secondary priced at $39.42 Acadia Healthcare (ACHC) Q3 adj EPS in-line at $0.72; Q3 revs $587.6M vs. est. $590.9M; Q3 same facility revenue increased 7.9% YoY, including an increase in revenue per patient day of 5.6% and an increase in patient days of 2.2%; same facility adjusted EBITDA margin was 29.0%; narrowed 2021 revenue to $2.295B-$2.315B vs. est. $2.31B CareDX (CDNA) Q3 adj EPS 7c vs est. 1c on revenue $75.6M vs est. $74M; raised FY21 revenue forecast to $290M-$293M from $280M-$290M DaVita Inc. (DVA) 3Q EPS $2.36 vs est. $2.25 on revs $2.94B, says US dialysis treatments averaged 94,509/day; guides FY adj EPS $8.80-9.15 vs est. $9.19 Dexcom (DXCM) Q3 EPS $0.71 vs. est. $0.63; Q3 revs $650.2M vs. est. $617.82; Based on the strong third quarter results, Dexcom is increasing its guidance for fiscal year 2021 revenue, Non-GAAP gross profit margin, Non-GAAP operating margin, and Adjusted EBITDA margin Gilead Sciences (GILD) 3Q adj EPS $2.65 vs est. $1.75 on revs $7.4B vs est. $6.3B; guides FY total product sales $26-26.3B vs est. $25.14B (sees $21.5B ex Veklury); guides FY adj EPS $7.90-8.10 vs est. $7.19 Nextgen health (NXGN) 2Q adj EPS $0.29 vs est. $0.23 on revs $149.3Mm vs est. $143.4Mm; guides FY revs $584-590Mm vs est. $582.4Mm, sees FY adj EPS $0.90-0.96 vs est. $0.93; says may repurchase up to $60Mm of its outstanding shares through March 2023 PTC Therapeutics (PTCT) Q3 EPS loss ($1.89) vs. est. loss ($1.40); Q3 revs $139M vs. est. $126.44M; raises FY21 rev view for DMD franchise to $400M-$420M from $370M-$390M and narrows R&D and SG&A expenses to $815M-$835M from $825M-$855M. ResMed (RMD) 1Q EPS $1.39 vs est. $1.36 on revs $904Mm vs est. $860.9Mm Seagen (SGEN) Q3 EPS ($1.61) vs est. $(0.58) on revenue $424.1M vs est. $383.1M, total net product sales $366.5M (+37% YoY) Stryker (SYK) Q3 adj EPS $2.20 vs. est. $2.28; Q3 revs $4.16B vs. est. $4.23B; Q3 organic net sales increased 4.5%; raises FY21 adjusted EPS view to $9.08-$9.15 from $8.80-$9.20 (est. $9.30); said now expect 2021 organic net sales growth to be in the range of 7% to 8% from 2019 Industrials & Materials Eastman Chemical (EMN) 3Q adj EPS $2.46 vs est. $2.46 on revs $2.72B vs est. $2.6B; guides FY EPS $8.80-9.00 vs est. $9.09, sees FY FCF about $1.1B; says implementing price increases across specialty product lines to offset higher costs, expect to be caught up in early 2022 Ecolab (ECL) to acquire Purolite, a leading global provider of fast-growing, high value separation and purification solutions to life sciences and critical industrial markets; Ecolab to pay approximately $3.7 billion in cash Fortive (FTV) Q3 adj EPS $0.66 vs. est. $0.65; Q3 revs $1.3B vs. est. $1.32B; raises FY21 adj EPS view to $2.70-$2.75 from $2.65-$2.75 (est. $2.72); said Delivered significant margin improvement, strong adjusted operating margin expansion and robust cash flow growth Hub Group (HUBG) Q3 EPS $1.28 vs est. $1.10 on in-line revs $1.08B; raises FY21 EPS $3.90-$4 from $3.50-$3.70 vs est. $3.66, still sees rev growth in the high-teens Huntington Ingalls (HII) 2Q adj EPS $1.71 vs est. $1.17 on revs $537Mm vs est. $375.6Mm L3Harris Technologies (LHX) raises FY21 adjusted EPS view to $12.85-$13.00 from $12.80-$13.00 and lowers FY21 revenue view to approximately $17.9B from $18.1B-$18.5B Mercer Int’l (MERC) 3Q EPS $1.04 vs est. $0.83 on revs $469.7Mm vs est. $452.9Mm Polymetal International PLC (POLY) 2Q adj EPS $0.77 vs est. $0.56 on revs $419Mm vs est. $428.4Mm; guides FY adj EPS $2.30-2.70 vs est. $3.10, sees FY revs $1.675-1.725B vs est. $1.8B Republic Service (RSG) 3Q adj EPS $1.11 vs est. $1.05 on revs $2.93B vs est. $2.84B; guides FY adj EPS $4.10-4.13 from prior $4.00-$4.05 and vs est. $4.05 Terex Corp. (TEX) 3Q EPS $0.67 vs est. $0.72 on sales $993.8Mm vs est. $1.0B; guides FY sales $3.85B vs est. $3.86B, sees FY EPS $2.75-2.85 vs est. $2.82 Werner Enterprise (WERN) Q3 EPS $0.94 vs. est. $0.95; Q3 revs $702.9M vs. est. $700.8M S. Steel (X) announces a $300 million stock repurchase program and increases its quarterly dividend to $0.05 per share; Q3 adjusted EPS $5.36 tops consensus $4.85; Q3 revs $5.96B vs. est. $5.79B

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Thursday, October 28, 2021 Futures Up/Down % Last Dow 54.00 0.15% 35,443 S&P 500 11.25 0.26% 4,556 Nasdaq 74.50 0.47% 15.662 U.S. futures are looking at a rebound after a late day swoon erased record gains for stocks, as markets again await another earnings barrage, with yesterday and today the two busiest days of the quarter. Drama out of Washington D.C. also adding to the volatility as investors remain hopeful on a spending bill. As for Wednesday, a midday all-time high for the Nasdaq 100 was marred by a late day sell-off in U.S. stocks, as the S&P 500 and Dow each retreated from records set just the previous day, led by weakness in energy stocks as oil prices tumbled from 7-year highs and long-dated Treasury yields also slumped, with the 30-year falling as much as 10bps below 2%. Corporate earnings have generally been better-than-expected, but constant reminders about rising costs, supply-chain issues, and labor shortages on conference calls brings into question the strength of markets going forward. Couple that with expectations for the Fed to begin its asset tapering plans in November and chances of interest rate hikes in mid-2022 to help prevent inflation getting further out of hand remains a market concern. Shares of Dow components McDonald’s, Coca-Cola and Microsoft rallied behind strong earnings. In fact, the Nasdaq outperformed behind large cap winners (TSLA, GOOGL MSFT, AMZN), though breadth was decisively negative and SmallCaps plunged with the Russell 200 falling nearly 2%. President Biden’s infrastructure and social-spending plans still remain “up-in-the-air” which also adds uncertainty. In Asian markets, The Nikkei Index fell about 1% to 28,820, the Shanghai Index slipped -1.23% to 3.518 and the Hang Seng Index dipped about -0.25% to 25,555. In Europe, the German DAX is down -0.15% at 15,680, while the FTSE 100 is also down roughly -0.2% at 7,240. Market Closing Prices Yesterday The S&P 500 Index dropped -23.11 points, or 0.51%, to 4,551.68 The Dow Jones Industrial Average fell -266.19 points, or 0.74%, to 35,490.69 The Nasdaq Composite little changed, or 0.00%, to 15,235.84 The Russell 2000 Index declined -43.58 points, or 1.90% to 2,252.49 Events Calendar for Today 8:30 AM ET Weekly Jobless Claims…est. 290K 8:30 AM EST Continuing Claims…est. 2.415M 8:30 AM ET Gross Domestic Product (GDP) for Q3-A…est. 2.7% (down from prior) 8:30 AM ET GDP Consumer Spending for Q3-A…prior month 12.0% 8:30 AM ET GDP Price Deflator for Q3…est. 5.5% 8:30 AM ET Core-PCE Prices Advance for Q3…est. 4.5% 10:00 AM ET Pending Home Sales MoM for September…est. 0% 10:30 AM ET Weekly EIA Natural Gas Inventory Data 11:00 AM ET Kansas City Fed Manufacturing for October 1:00 PM ET U.S. to sell $62 bln 7-year notes Earnings Calendar: Earnings Before the Open: AB, ABMD, ADS, AEP, AGCO, ALNY, AMT, AOS, ATI, BAX, BC, BSIG, BTU, CARR, CAR, CBRE, CBZ, CFR, CG, CMCO, CMCSA, CMS, CNX, COLB, CONE, COOP, COR, CWT, DBD, EME, EXP, FCN, GPI, GVA, HBAN, HSY, IBP, ICE, ITW, KBR, KDP, KEX, LECO, LH, LKQ, MA, MCO, MDD, MO, MRK, NEM, NLSN, NOC, OSK, OSIS, OSTK, PBF, RGEN, RLGY, RS, SAH, SAIA, SNDR, SWI, SWK, TAP, TFX, TPX, TREE, TW, TXT, VC, VLY, WEX, WST, XEL, YUM Earnings After the Close: AAPL, ABCB, ACHC, AGL, AMZN, ASPN, ATEN, ATR, AVT, AX, BIO, BY, CDNA, CHE, COHU, COLM, CPT, CUZ, CWST, DECK, DVA, DXCM, EB, EMN, FISI, FTDR, FTV, GILD, HIG, HUBG, LOPE, LPLA, LTC, NGRC, MHK, MMSI, MPWR, MSTR, NATI, NXGN, PEB, POWI, PSB, PTCT, QUMU, RMD, RSG, SBCF, SBUX, SGEN, SKX, SKYW, SM, SPNE, SSNC, SYK, TEX, TXRH, VCRA, VRSN, WDC, WRAP, WRE, X, ZEN Macro Up/Down Last Nymex -1.61 81.05 Brent -1.37 83.21 Gold -2.10 1,801.20 EUR/USD -0.0006 1.1598 JPY/USD -0.23 113.57 10-Year Note +0.012 1.541% Sector News Breakdown Consumer eBay Inc. (EBAY) 3Q adj EPS $0.90 vs est. $0.89 on revs $2.5B vs est. $2.46B; guides 4Q adj EPS $0.72-0.76 vs est. $1.00, sees 4Q revs $2.57-2.62B vs est. $2.65B; raising estimated FY share buyback from $5.0B to $7.0B Ford Motor (F) announces resumption of stock dividend in 4q; 3Q adj EPS $0.51 vs est. $0.27 on revs $35.7B vs est. $32.5B; expects cash flow over current planning period to be more than sufficient to fund growth, announces resumption of regular stock dividend in 4Q; no changes to FY adj FCF guide of $4.0-5.0B Boot Barn (BOOT) Q2 EPS $1.25 vs est. $0.93 on revenue $312.7M (+67.1% vs 2Q19) vs est. $291M, same-store sales +61.7% YoY, +53.6% vs 2019; sees new unit growth 10% in FY22; named Jim Watkins as CFO with current CFO Greg Hackman continuing as VP and COO Churchill Downs (CHDN) 3Q EPS $1.57 vs est. $1.47 on revs $393Mm vs est. $406.8Mm Fresh Del Monte Produce Inc. (FDP) said it is raising prices on bananas, pineapples and fresh-cut fruit in response to unprecedented market conditions and inflationary pressures being felt across all industries iRobot (IRBT) Q3 EPS $1.67 vs. est. $0.70; Q3 revs $440.7M vs. est. $417.04M; cuts FY21 non-GAAP EPS view to $1.15-$1.74 from $2.25-$3.15 (est. $2.70) and lowers FY21 revenue view to $1.56B-$1.59B from $1.55B-$1.62B (est. $1.58B) Noodles (NDLS) Q3 adj EPS 12c vs est. 9c on in-line revenue $125.1M with digital sales 52% of total revs; system-wide comp sales +16.3% vs est. +14.3%, avg unit volume $1.38M, +16% YoY; now sees 7-9 new restaurants in 2021, down from prior outlook for 10-15; anticipates system-wide unit growth of at least 8% next year O’Reilly Auto (ORLY) Q3 EPS $8.07 vs. est. $7.18; Q3 sales $3.48B vs. est. $3.3B; gross profit margin 52.3% vs. 52.4% y/y; raises year rev outlook to $12.9B-$13.2B from prior $12.3B-$12.6B (est. $12.73B) Sleep Number (SNBR) 3Q EPS $2.22 vs est. $1.44 on revs $640Mm vs est. $587.1Mm; sees FY EPS $7.25 vs est. $7.15; Spirit Airlines (SAVE) Q3 adj EPS ($0.69) was a narrower loss than est. ($1.02) on in-line revs $922.6M; load factor 77.6%, capacity +3.5% vs 3Q19; is slowing the pace to push back to full fleet utilization, expects to produce 53B-55B available seat miles in 2022 VICI Properties (VICI) 3Q adj FFO/shr $0.45 on revs $375.7Mm; guides FY adj FFO/shr $1.7901.80 vs est. $1.84 Wyndham Hotels (WH) 3Q EPS $1.09 vs est. $0.91 on net revs $463Mm vs est. $463Mm; guides FY RevPAR growth about 43%, sees fee-related and other revs $1.21-1.23B; guides FY adj EPS $2.93-3.03 vs est. $2.69 Yum China (YUMC) Q3 adj EPS $0.22 vs. est. $0.31; Q3 revs $2.55B vs. est. $2.51B; qtrly total system sales increased 1% year over year, with increases of 1% at both KFC and Pizza Hut, excluding f/x; increasing gross new stores target to over 1,700 in 2021; expect that covid-19, especially the delta variant outbreaks, will continue to affect consumer behavior and impact our same-store sales recovery. Solo Brands, Inc. (DTC) prices 12.9M share IPO at $17.00 per share Scientific Games Corp (SGMS) announces sale of lottery business to Brookfield business partners for $6.05 billion; deal consisting of $5.825 bln in cash & an earn-out of up to $225 mln based on achievement of certain ebitda targets in 2022 & 2023 Energy, Industrials & Materials Allison Transmission (ALSN) 3Q EPS $0.89 vs est. $0.90 on revs $567Mm vs est. $584Mm; guides FY sales $2.325-2.4B vs est. $2.36B Flowserve Corp. (FLS) 3Q adj EPS $0.29 vs est. $0.40 on revs $866.1Mm vs est. $899Mm; guides FY revs down 2-4% vs est. -2.3%, sees FY EPS $1.45-1.65 (was $1.40-1.45) vs est. $1.58, sees CAPEX $70-80Mm vs prior $65Mm Kraton (KRA) Q3 adj EPS $0.98 vs. est. $0.79; Q3 revs $526.9M vs. est. $459.1M; Polymer segment operating income of $43.8 million, compared to an operating loss of $5.1 million YoY; Chemical segment operating income of $35.7M, compared to an operating loss of $401.7M YoY Sunnova Energy (NOVA) Q3 EPS ($0.25) vs est. ($0.13) on revenue $68.9M vs est. $67.4M; reaffirmed FY21 view for adj EBITDA $80M-$85M, customer additions 55k-58k; set FY22 guidance for adj EBITDA $117M-$137M, customer additions 83k-87k Tronox Holdings (TROX) Q3 adj EPS $0.72 vs. est. $0.64; Q3 revs rose 29% to $870M vs. est. $905.3M United Rentals (URI) 3Q adj EPS $6.58 vs est. $6.80 on revs $2.6B vs est. $2.58B; guides FY revs $9.6-9.75B vs est. $9.6B, sees FY adj EBITDA $4.325-4.4B vs est. 4.3B Financials Aflac (AFL) Q3 adj EPS $1.53 vs. est. $1.32; Q3 revs $5.2B vs. est. $5.34B; in yen terms, Aflac Japan’s net premium income was ¥323.1 bln for quarter, or 4.0% lower than a year ago AvalonBay (AVB) Q3 core FFO $2.06 vs est. 1.97, EPS $0.56 vs est. $0.77, same-store sales +1.2%; sees Q4 core FFO $2.19-$2.29 vs est. $2.11, raised FY core FFO view to $8.18-$8.28 from $7.92-$8.12 CyrusOne Inc. (CONE) 3Q adj FFO/shr $1.02 vs est. $0.99 on revs $304.1Mm vs est. $290.4Mm; guides FY revs $1.18-1.2B vs est. $1.17B Invitation Homes (INVH) Q3 core FFO 38c/shr vs est. 36c, EPS 12c vs est. 10c, revenue $510M vs est. $497.8M; same-store NOI +11.9% YoY on same-store revs +7.9%; raised FY21 core EPS view to $1.49 at midpoint from $1.44, adj FFO ro $1.28 at midpoint from $1.24 Lending Club (LC) Q3 EPS $0.26 vs est. $0.03 on revenue $246.2M vs est. $221.2M; sees Q4 revs $240M-$250M vs est. $235.7M, loan originations $2.8-$3B; raised FY view for revenue to $796M-$806M from $750M-$780M Raymond James (RJF) Q4 EPS $2.06 vs. est. $1.71; Q4 revs $2.7B vs. est. $2.54B; quarter-end records for client assets under administration of $1.18 trillion, financial assets under management of $191.9B, and net loans at Raymond James Bank of $25B The SEC asked at least one asset manager not to proceed with plans for a leveraged bitcoin exchange-traded fund, according to a person familiar with the matter. The SEC indicated it wants to limit new bitcoin-related products to those that provide unleveraged exposure to bitcoin futures contracts, such as the ProShares Bitcoin Strategy exchange-traded fund, which was launched last week, the person said. https://on.wsj.com/3GvG2qg Healthcare Align Technology (ALGN) 3Q adj EPS $2.87 vs est. $2.60 on revs $1.02B vs est. $978Mm; guides FY revs $3.9-3.95B vs est. $3.94B; says clinical study validates benefits of the Itero Element 5D imaging system Alnylam (ALNY) reports positive topline 18-month results from Helios-a phase 3 study of Vutrisiran in patients with HATTR amyloidosis with polyneuropathy BioMarin (BMRN) Q3 GAAP EPS loss (-$0.20) vs. est. loss (-$0.25); Q3 revs $408.7M vs. est. $435.32M; Lower Kuvan product revenues primarily due to generic competition due to the loss of exclusivity in the U.S.; Lower Aldurazyme product revenues due to timing of product fulfillment to Genzyme Edwards LifeSciences (EW) Q3 EPS $0.54 vs. est. $0.53; Q3 revs $1.3B vs. est. $1.32B; sees FY21 adjusted EPS at high end of $2.07-$2.27 (est. $2.26) and reaffirms FY21 revenue view $5.2B-$5.4B (est. $5.32B); TAVR sales grew 15%; underlying 14%; U.S. TAVR sales grew 12%; OUS approximately 20% Encompass Health (EHC) Q3 adj EPS $1.03 vs. est. $1.06; Q3 revs $1.28B vs. est. $1.31B; cuts FY21 adj EPS view to $4.23-$4.38 from $4.32-$4.47 and lowers FY21 revenue view to $5.08B-$5.13B from $5.1B-$5.25B (est. $5.18B) Molina Healthcare (MOH) Q3 adj EPS $2.83 vs. est. $2.79; Q3 revs $7.04B vs. est. $6.79B; backs FY21 EPS view of no less than $13.25 vs. est. $13.38 and backs FY21 revenue view of no less than $27.5B vs. est. $26.97B; consolidated MCR for Q3 was 88.9%, compared to 85.9% in the third quarter of 2020 Teladoc (TDOC) Q3 EPS loss (-$0.53) vs. est. loss (-$0.65); Q3 revs $521.66M vs. est. $516.6M; Q3 visits topped 3.9M, 37% higher than Q3 2020; sees Q4 EPS loss (73c)-(53c) vs. est. loss (69c); sees Q4 revs $536M-$546M vs. est. $539.74M; sees Q4 total visits 3.9M-4.1M

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Monday, October 18, 2021 U.S. equity futures are looking lower after posting strong gains last week, with oil prices extending their near-term rally into a ninth consecutive week, as concerns over surging inflation pressures and the weakest China growth rate in more than a year tamed optimism linked to a strong start to the third quarter earnings season. Chinese Q3 GDP missed, rising +0.2% q/q vs 0.5% consensus, and was +4.9% y/y vs 5.2% consensus amid a rolling power crisis, supply chain disruptions and a crackdown on the tech sector. In the U.S., the earnings flood begins this week with 72 names in the S&P 500 expected to report quarterly results this week. In corporate news today, Apple (AAPL) is holding its second major launch event of the Fall where it is expected to unveil the first redesign of its MacBook Pro laptop in at least five years (starts at 1:00 PM ET). In Asian markets, The Nikkei Index dipped -43 points to 29,025, the Shanghai Index slipped a few points to settle at 3,568, and the Hang Seng Index rose 78 points to 25,409. In Europe, the German DAX is lower by -0.6% or nearly 100-points to drop below 15,500, while the FTSE 100 dips -0.3% to hold above the 7,200 level. U.S. stocks look to build on last week’s gains where large-cap tech names propelled the advance Friday, with shares of Amazon.com (AMZN) and Tesla (TSLA) each rising more than 3% on no specific news, while the SmallCap Russell 2000 underperformed, falling -0.35% as investors bailed on value stocks for growth stocks. Strong quarterly earnings from Dow component Goldman Sachs (GS) also boosted financials as investors prepare for a flood of reports next week. Shares of cryptocurrency and blockchain-related firms gained last week as bitcoin topped $60,000 for the first time since April, with expectations growing that U.S. regulators would allow a futures-based ETF. Market Closing Prices Yesterday The S&P 500 Index jumped 33.11 points, or 0.75%, to 4,471.37 The Dow Jones Industrial Average rose 382.20 points, or 1.09%, to 35,294.76 The Nasdaq Composite climbed 73.91 points, or 0.50%, to 14,897.34 The Russell 2000 Index declined -8.52 points, or 0.37% to 2,265.65 Events Calendar for Today 9:15 AM ET Industrial Production MoM for September…est. +0.2% 9:15 AM ET Capacity Utilization for September…est. 76.5% 10:00 AM ET NAHB Housing Market Index for October…est. 76 4:00 PM ET Net Long-term TIC Flows for August Earnings Calendar: Earnings Before the Open: ACI, GNTY, STT Earnings After the Close: CFB, ELS, FBK, FNB, HXL, PACW, SFBS, STLD, ZION Other Key Events: Apple (AAPL) announces October 18th event (New MacBooks, a Mac Mini, and AirPods are anticipated) Macro Up/Down Last Nymex 1.43 83.71 Brent 1.11 85.97 Gold -6.70 1,763.50 EUR/USD -0.0012 1.1586 JPY/USD 0.15 114.37 10-Year Note +0.042 1.618% World News China’s industrial output rose +3.1% in September from a year earlier, missing expectations of up +4.5%, and slowing from 5.3% in August, official data showed. Retail sales grew +4.4% in September on-year, compared with a forecast 3.3% increase and a 2.5% rise in August. Fixed asset investment increased +7.3% in the first nine months from the same period a year earlier, missing expectations for a +7.9% rise Chinese Q3 GDP missed, rising +0.2% q/q vs 0.5% consensus; +4.9% y/y vs 5.2% consensus; Chinese Q3 GDP YTD missed +9.8% y/y vs 10.1% consensus; Chinese Sep Unemployment Rate lower: 4.9% vs 5.1% consensus Sector News Breakdown Consumer Lennar ($LEN) said its board increased share repurchase authorization by up to the lesser of $1 billion in purchase price, or 25 million in shares, of the outstanding Class A or Class B common stock Zillow Group ($ZG) is taking a break from buying U.S. homes after the online real estate giant’s pivot into tech-powered house-flipping hit a snag, Bloomberg reported saying after buying more than 3,800 homes in Q2, it will stop pursuing new home purchases as it works through a backlog of properties already in its pipeline Energy, Industrials and Materials S. crude oil futures closed at fresh seven-year highs last week at $82.28 for WTI crude and $8.86 for Brent as a natural gas supply crunch in Europe and optimism about demand in the U.S. continued to propel the recent rally. For the week, WTI rose 3.7% and Brent added 3%, the eighth straight weekly gain for both. Occidental Petroleum ($OXY) upgraded to Buy from Hold at Truist Steel Dynamics ($STLD) downgraded to Equal Weight from Overweight at Morgan Stanley and firm also downgraded S. Steel (X) to Underweight from Equal Weight Virgin Galactic ($SPCE) downgraded to Sell from Neutral at UBS with $15 tgt Healthcare Biogen Inc’s ($BIIB) said a late-stage experimental treatment for an inherited form of amyotrophic lateral sclerosis (ALS) failed to reach its main goal, but secondary measures and biomarkers showed favorable trends. Tofersen is designed to suppress the production of SOD1, a protein that can accumulate to toxic levels in ALS patients with mutations in a specific gene. Revance ($RVNC) shares fell over -30% late Friday after the FDA declined to approve its frown line injection treatment, citing issues with the company’s manufacturing facility; o other concerns were raised by the agency Avadel ($AVDL) shares slide over -20% after saying the U.S. FDA notified the co that the agency is still reviewing the marketing application of its sleep disorder drug, FT218, and the decision will likely not be taken this month (prior review was expected by Oct. 15) Omeros Corporation ($OMER) said they received a Complete Response Letter (CRL) from the U.S. FDA regarding its Biologics License Application ($BLA) for narsoplimab in the treatment of hematopoietic stem cell transplant-associated thrombotic microangiopathy ($HSCT-TMA). PTC Therapeutics ($PTCT) downgraded to Underperform from Neutral at Bank America with a $38 price target Oyster Point Pharma ($OYST) announced that the FDA has approved Tyrvaya Nasal Spray 0.03 mg for the treatment of the signs and symptoms of dry eye disease MeiraGTx ($MGTX) mentioned positively in Barron’s saying shares could more than double as the company will present its gene-regulating “switches” at next week’s conference of the European Society of Gene and Cell Therapy, and to Wall Street investors in mid-December. Notes shares have fallen from a 2019 peak of $30 to a recent $14, leaving its market cap below $600 million The plan to roll out Merck & Co’s ($MRK) promising antiviral pill to treat COVID-19 risks repeating the inequities of vaccine distribution, potentially leaving the nations with the greatest need once again at the back of the line, international health groups say – Reuters Technology, Media & Telecom Dell Inc. ($DELL) with a positive mention in Barron’s saying the company is about to become much more attractive to investors as it prepares to spin off its valuable stake in software maker VMware (VMW) in early November, arguing that Dell will emerge with a solid balance sheet and simpler structure. Netflix ($NFLX) estimates that its latest megahit, “Squid Game,” will create almost $900 million in value for the company, and only cost about $21M to make. Netflix estimates that 89% of people who started the show watched at least 75 minutes – more than one episode – and 66% of viewers, or 87 million people, have finished the series in the first 23 days Disney ($DIS) downgraded to Equal Weight from Overweight at Barclays and cut tgt to $175 from $210 Members of a congressional committee questioned whether Amazon (AMZN) executives misled them during an investigation of the company’s business practices and if they may have lied under oath – WSJ reports Upstart ($UPST) downgraded to Underperform from Neutral at Bank America saying the LT thesis intact, but near-term upside priced in

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/*============================================= = Friday, June 11, 2021 = =============================================*/ Futures Up/Down % Last Dow 75.00 0.22% 34,429 S&P 500 4.25 0.11% 4,233 Nasdaq 13.50 0.09% 13,963 Stock futures are looking higher, trying to build off yesterday’s gains as the S&P 500 Index posted its first closing high in over a month and as the Nasdaq Composite outperformed (rising over 0.75%) as the yield on the benchmark 10-year yield fell to its lowest levels since March, now down around the 1.43% level. Market fears of rising prices and inflation have deteriorated despite another spike in CPI yesterday when prices topped 5% on YoY basis, its highest levels since 2008 as investors hang on to the notion (implied by the Fed) that the price hikes are indeed transitory. Market gains were paced by strong gain in healthcare and REITs. In Asian markets, The Nikkei Index fell -9 points to 28,948, the Shanghai Index slid -21 points to 3,589, and the Hang Seng Index rose 103 points to 28,842. In Europe, the German DAX is up about 40 points to 15,610, while the FTSE 100 is higher by 45 points to 7,133. Market Closing Prices Yesterday The S&P 500 Index gained 19.63 points, or 0.47%, to 4,239.18 The Dow Jones Industrial Average rose 19.10 points, or 0.06%, to 34,466.24 The Nasdaq Composite jumped 108.58 points, or 0.78%, to 14,020.33 The Russell 2000 Index declined -15.72 points, or 0.68% to 2,311.41 Events Calendar for Today 10:00 AM EST University of Michigan Sentiment June-P 1:00 PM EST Baker Hughes Weekly rig count data Other Key Events: FBN Securities Silicon Valley Tech Tour (virtual), 6/10-6/11 Oppenheimer Virtual Software & Semiconductor Bus Tour, 6/7-6/11 Macro Up/Down Last Nymex 0.13 70.42 Brent 0.14 72.66 Gold -6.00 1,892.50 EUR/USD -0.0014 1.2156 JPY/USD 0.16 109.49 10-Year Note -0.021 1.437% World News The U.S. Senate Commerce Committee unveiled on Thursday a bipartisan surface transportation bill that would authorize $78 billion over five years, including sharply higher passenger rail funding, along with tougher auto safety requirements. Ten Senate Democrats and Republicans say they reached five-year, nearly $1 trillion infrastructure deal ‘; agreement calls for about $974 bln in infrastructure spending over five years without raising taxes. The package includes about $579 bln in new spending. UK Apr GDP beat m/m: 2.3% m/m vs 2.2% cons; 3m/3m 1.5% in-line; y/y 27.6% in-line; UK April Trade Balance smaller deficit: -£10.96b vs -£12.1b consensus; UK Apr Trade Balance non-EU smaller deficit: -£5.55b vs -£6.54b previous Sector News Breakdown Consumer Chewy ($CHWY) 1Q EPS $0.09 vs. est. ($0.03) on sales $2.14B vs. est. $2.13B; Gross margin of 27.6% expanded 420 bps YoY; net margin of 1.8% improved 480 bps YoY; Q1 adjusted EBITDA of $77.4M; Q1 active customers 19.8M, up 31.6% from last year Dave & Busters ($PLAY) Q1 EPS $0.40 vs. est. loss (-$0.19); Q1 revs $265.3M vs. est. $256.6M; Q1 comp store sales fell -35%; sees Q2 revs $335M-$350M vs. est. $287.4M Copa Holdings ($CPA) reports revenue passenger miles dropped 58% to 753.6M in May 2021 vs. May 2019; capacity down 53.4% to 970.9M available seat miles as compared to May 2019 Energy, Industrials and Materials The IEA forecasts global oil demand to recover to pre-pandemic levels late next year and urged OPEC and its allies to keep markets balanced by tapping their plentiful spare production capacity Livent ($LTHM) 13M share Secondary priced at $17.50 REV Group ($REVG)5M share Secondary priced at $15.50 Navigator Holdings ($NVGS) Q1 EPS $0.05 vs. est. $0.05; Q1 revs $85.7M vs. est. $71.29M Financials AGNC Investment ($AGNC) estimates tangible net book value per share of $16.82 as of May 31, 2021, down 6.4% from $17.96 it estimated at April 30. Agree Realty ($ADC) 4M share Spot Secondary priced at $71.50 Manning & Napier ($MN) reports preliminary AUM $22.1B as of May 31 Victory Capital Holdings, Inc. ($VCTR) reported assets under management (AUM) of $160.9 billion as of May 31, 2021 TaskUs ($TASK)2M share IPO priced at $23.00 Healthcare Vertex Pharma ($VRTX) shares declined over 10% after abandoning further development of VX-864 for alpha-1 antitrypsin deficiency saying that the treatment benefit seen in a phase 2 study is “unlikely to translate into substantial clinical benefit.” Jury selection began this week in a case considered one of the biggest and most complicated in the effort to hold corporations liable for the opioid crisis according to Barron’s. The trial, in New York, was delayed a year because of the pandemic. New York state and two of its counties, Nassau and Suffolk on Long Island, are suing a number of companies, including Johnson & Johnson (JNJ), McKesson ($MCK) and Teva Pharmaceutical ($TEVA), for monetary damages Tyme Technologies, Inc. ($TYME) completes strategic review, announces oasis breast trial with Georgetown University, and reports fiscal year 2021 financial results; review identified breast cancer as a priority indication for development, a focus on second-line pancreatic cancer, and continuation of trial in high-risk sarcomas CureVac ($CVAC) slides; The efficacy of CureVac’s Covid-19 vaccine is still hard to determine but is set to remain in focus as critical data from the phase 3 trial is expected this month, Berenberg says. Analysts at the bank say the trial’s progress seems encouraging and could facilitate a rapid regulatory discussion in the coming months. They expect the CVnCoV vaccine to be 70% to 80% effective – DJ PTC Therapeutics ($PTCT) announced interim results from the ongoing RAINBOWFISH trial that demonstrated pre-symptomatic infants with spinal muscular atrophy, or SMA Vertex Pharmaceuticals ($VRTX) and CRISPR Therapeutics ($CRSP) announce new data on 22 patients, with follow-up of at least 3 months, treated with CRISPR/Cas9-based gene-editing therapy, CTX001 Technology, Media & Telecom Nvidia ($NVDA) has agreed to acquire DeepMap, a startup committed to building high-definition maps for autonomous vehicles to navigate the world safely Didi Chuxing, China’s biggest ride-hailing firm, made public the filing for its long-anticipated U.S. stock market listing, setting the stage for what is expected to be the world’s biggest initial public offering this year. SeaChange ($SEAC) 1Q adj EPS ($0.07) vs. est. ($0.09) on revs $5.1Mm vs. est. $4.9Mm; qtr end backlog $20.1Mm

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Key Metrics

Market Cap

2.17 B

Beta

0.94

Avg. Volume

635.19 K

Shares Outstanding

71.34 M

Yield

0%

Public Float

0

Next Earnings Date

2022-07-28

Next Dividend Date

Company Information

PTC is a science-driven, global biopharmaceutical company focused on the discovery, development and commercialization of clinically differentiated medicines that provide benefits to patients with rare disorders. PTC's ability to globally commercialize products is the foundation that drives investment in a robust and diversified pipeline of transformative medicines and its mission to provide access to best-in-class treatments for patients who have an unmet medical need. The Company's strategy is to leverage its strong scientific expertise and global commercial infrastructure to maximize value for its patients and other stakeholders.

CEO: Stuart Peltz

Website:

HQ: 100 Corporate Ct South Plainfield, 07080-2400 New Jersey

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