$TBPH

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Upgrades 9/16: $AXP $AZUL $BUD $CAR $CSCO $DAN $DASH $SAN $SIG Downgrades 9/16: $BYND $EQNR $FSR $GMAB $LEA $LVS $MLCO $RIDE $TBPH $UL $VC $WYNN +Initiations 9/16: $AUUD $CELH $CRNT $EZPW $GXO $HUMA $LILM $LMAT $PEN

Wednesday, September 15, 2021 Futures Up/Down % Last Dow 20.00 0.06% 34,484 S&P 500 6.25 0.14% 4,441 Nasdaq 34.50 0.22% 15,414 S&P futures are higher as major averages look to rebound from selling pressure yesterday that saw all 11 sectors close in the red, with basic materials and industrials being the largest losers, followed not far behind by financials which dropped on cautious trading commentary from various banks at a sell-side conference and a drop in Treasury yields as CPI inflation data for August was tamer than expected. Healthcare and technology were among the sectors that faced the least downside pressure. Megacaps were mixed at the close as Apple ($AAPL) continues to fade even after it unveiled the much-awaited iPhone 13, managing to settle just above its 50-day moving average. U.S. listed China stocks tumble again overnight, led by declines in the casino/gaming sector on stricter restrictions. Overnight, Microsoft ($MSFT) board approves new share buyback of up to $60B in shares; raises quarterly dividend 11% to 62c per share. Overseas, China economic data disappointed across the board as monthly retail sales came in well below views, along with misses in industrial production and as China’s new home prices grew at their slowest pace in eight months. In Asian markets, The Nikkei Index fell -158 points to 30,511, the Shanghai Index dipped -6 points to 3,656, and the Hang Seng Index declined -469 points to 25,033. In Europe, the German DAX is down about -15 points to 15,705, while the FTSE 100 is up a few points at 7,040. Busy morning of economic data with manufacturing, import prices and industrial production on the calendar. Market Closing Prices Yesterday The S&P 500 Index dropped -25.68 points, or 0.57%, to 4,443.05 The Dow Jones Industrial Average fell -292.06 points, or 0.84%, to 34,577.57 The Nasdaq Composite slumped -67.82 points, or 0.45%, to 15,037.76 The Russell 2000 Index declined -30.80 points, or 1.37% to 2,209.98 Events Calendar for Today 7:00 AM ET MBA Mortgage Applications Data 8:30 AM ET Empire Manufacturing for September…est. 18.0 8:30 AM ET Import Prices MoM for Aug…est. +0.3% 8:30 AM ET Export Prices MoM for Aug…est. +0.4% 9:15 AM ET Industrial Production MoM for Aug…est. 0.4% 9:15 AM ET Capacity Utilization for Aug…est. 76.4% 10:30 AM ET Weekly DOE Inventory Data Earnings Calendar: Earnings Before the Open: WEBR Earnings After the Close: none Other Key Events: Barclay’s Financial Services Conference (virtual) 2021, 9/13-9/15 Citigroup 2021 Global Technology Conference (virtual), 9/13-9/15 Piper 2021 D.C. Bank Field Trip, 9/13-9/15 Baird Global Healthcare Conference 2021 (virtual), 9/14-9/15 Barclay’s Financial Services Conference (virtual) 2021, 9/13-9/15 HC Wainwright 23rd Annual Global Investment Conference (virtual), 9/13-9/15 Jefferies Software Conference (virtual), 9/14-9/15 Lake Street 5th Annual Best Ideas Growth Conference (virtual), 9/14-9/15 Macro Up/Down Last Nymex 1.09 71.52 Brent 1.04 74.63 Gold -2.80 1,801.70 EUR/USD 0.0023 1.1826 JPY/USD -0.35 109.34 10-Year Note +0.00 1.279% World News China’s retail sales grew a disappointing5% in August from a year ago, well below the forecast for 7% growth, as the country dealt with the worst outbreak of Covid-19 since its initial spread in early 2020. Industrial production growth was also slightly below expectations, up 5.3% in August versus predictions of 5.8% growth China’s new home prices grew at their slowest pace in eight months in August, official data showed on Wednesday. Average new home prices in China’s 70 major cities grew 0.2% month-on-month in August after increasing 0.3% in July. Compared with a year earlier, China’s new home prices grew 4.2% in August, down from a 4.6% increase in July. North Korea launched two short-range ballistic missiles off its east coast on Wednesday, South Korean and Japanese officials said, as Pyongyang returns to weapons tests after saying that its patience for talking had worn thin. UK Aug CPI higher at +0.7% m/m vs 0.5% consensus, 3.2% y/y vs 2.9% consensus; UK Aug CPI Core higher at +0.7% m/m vs 0.4% cons, 3.1% y/y vs 2.9% consensus – U.K. inflation surge prompts bets for sharper rate increases Sector News Breakdown Consumer Yum China ($YUMC) said its adjusted operating profit would take a 50% to 60% hit in Q3 as the spread of the Delta variant in China led to restaurant closures and “sharply reduced sales”; says same-store sales in August declined by mid-teens percentage Y/Y, or close to an approximately 20% decline compared to August 2019 S. casinos with operations in Macau looking sharply lower for a second straight day as Macau government proposes to revise the city’s gaming law, tightening direct supervision of casinos in the world’s largest gambling hub. Reuters noted Macau’s secretary for economy and finance said there were still some deficiencies in industry supervision. P. Morgan downgraded Macau gaming names Galaxy Entertainment (GXYEF), MGM China (MCHVF) SJM Holdings (SJMHY), Melco (MLCO), Wynn Macau (WYNMF) and Sands China (SCHYY) from overweight to neutral or underweight due to heightened scrutiny on capital management and daily operations ahead of license renewals Academy Sports (ASO)645M share Secondary priced at $44.75 Leslie’s ($LESL)8M share Secondary priced at $22.00 DavidsTea ($DTEA) tumbled 25% after the tea retailer said its ecommerce and wholesale sales fell by nearly one-third in its fiscal second quarter European Wax Center ($EWCZ) guides FY21 revs $173-178Mm vs est. $178.2Mm, sees FY system-wide sales $788-793Mm; sees FY adj net income $26.5-28.5Mm Dutch Bros ($BROS) 21M share IPO priced at $23.00 On Holding ($ONON)1M share IPO priced at $24.00 Energy, Industrials and Materials Workhorse Group ($WKHS) shares fell after hours Tuesday as the co voluntarily dismissed its legal challenge against a U.S. Postal Service ($USPS) move to award a multibillion-dollar contract to Oshkosh Defense (OSK) for making postal delivery vehicles, Reuters reported The American Petroleum Institute ($API) showed a draw of 5.44M barrels of oil for the week ending September 10, while gasoline inventories showed a draw of 2.76M barrels, distillate inventories show a draw of 2.89M barrels and Cushing inventories show a draw of 1.36M barrels The first all-civilian mission to orbit Earth is set to take off tonight, within a five-hour launch window that opens at 8:02 p.m. ET. SpaceX will power the expedition, known as Inspiration4, using one of its Dragon capsules atop a reusable Falcon 9 rocket JinkoSolar ($JKS) Q2 EPS $0.22 vs. et. Loss (-$0.16); Q2 revs $1.23B vs. est. $1.22B; Q2 shipments were 5,203 MW; said total Q3 revenue is expected to be in range of $1.24B-$1.37B vs. est. $1.6B; for FY 2021, estimates total shipments (including solar modules, cells and wafers) to be in range of 25 GW-30GW FTC Solar ($FTCI) announced that Tony Etnyre will step down as CEO and board member; board has appointed Sean Hunkler as his successor effective Sep.24. Raytheon Technologies (RTX) has agreed to acquire advanced space electronics supplier SEAKR Engineering Financials BRP Group ($BRP) 8M share Secondary priced at $30.50 Capital One ($COF) reports August net charge-offs 1.54% vs. 1.45% last month and reports August 30-plus day delinquencies 1.79% vs. 1.71% last month Synchrony ($SYF) reported August charge-off rate 2.59% vs. 2.24% last month and also reports August 30-plus day delinquencies 1.33% vs. 1.37% last month The Federal Housing Finance Agency and the U.S. Department of Treasury suspend certain parts of the 2021 Preferred Stock Purchase Agreement with Fannie Mae (FNMA) and Freddie Mac (FMCC). “This suspension will provide FHFA time to review the extent to which these requirements are redundant or inconsistent with existing FHFA standards, policies, and directives that mandate sustainable lending standards,” said Acting Director Sandra L. Thompson CPI Card Group ($PMTS) files to sell 6.56M shares of common stock for holders Healthcare Dice Molecules Holdings ($DICE) 12M share IPO priced at $17.00 Procept BioRobotics ($PRCT)56M share IPO price $25.00 Tyra Biosciences ($TYRA)8M share IPO priced at $16.00 Pfizer ($PFE) is seeking FDA approval for use of its COVID-19 vaccine in children aged six months to five years, the Financial Times reports. The company is aiming to gain such approval in November Avalo Therapeutics ($AVTX)5M share Spot Secondary priced at $2.20 Sage Therapeutics ($SAGE) announced that the U.S. FDA has granted Fast Track Designation to SAGE-718 for development as a potential treatment for Huntington’s disease. Fast Track is a process designed to facilitate the development and review of new treatments for serious conditions with unmet medical need such as HD Theravance Biopharma ($TBPH) shares down over 30% after announcing its hypotension treatment did not meet main goal, halts non-respiratory disease related programs; also announces cost reduction program to focus on commercializing respiratory therapeutics to maximize shareholder value; will reduce the headcount by ~75%, which will result in annualized operating expense savings of ~$165M in 2022; Unicycive Therapeutics ($UNCY) will be added as a member of the Russell Microcap Index as part of the 2021 Russell indexes reconstitution after the market opens on September 20, 2021 Technology, Media & Telecom Microsoft ($MSFT) board approves new share buyback of up to $60B in shares; raises quarterly dividend 11% to 62c per share Skillsoft ($SKIL) raises FY22 revenue view to $670M-$690M from $645M-$675M and boosts FY22 bookings view to $690M-$710M from $660M-$690M; reaffirms FY22 adjusted EBITDA view $155M-$175M Live Nation (LYV)23M share Spot Secondary priced at $86.90 CS Disco (LAW)5M share Secondary priced at $53.00 Aspen Group (ASPU) 1Q EPS ($0.03) vs est. ($0.05) on revs $19.4Mm vs est. $19.2Mm Bentley Systems, Incorporated ($BSY) announced that its Seequent business unit has acquired Canadian software company Minalytix, the developer of MX Deposit. Sonim Technologies ($SONM) said it plans to effect a one-for-ten reverse split of its issued and outstanding common stock, effective Sep.15.

was just looking at that $TBPH chart

3963 $TBPH OCT2021 $10 Cs trade 1.1

3963 $TBPH OCT2021 $10 Cs trade 1.1

3881 $TBPH Oct21 10.0 Calls trade $1.10 (FT Theo=0.87) ASKSIDE [ARCA] IV=151.3% +19.8 FLOOR - OPENING Vol=4304, OI=3255,

Tuesday, August 24, 2021 Futures Up/Down % Last Dow 59.00 0.17% 35,340 S&P 500 8.25 0.19% 4,484 Nasdaq 45.50 0.30% 15,350 U.S. futures are looking higher, adding to the record setting performances by the S&P 500 and Nasdaq yesterday on further vaccine approval optimism yesterday, while China stocks rebound for the first time in 2-weeks. Last week’s stock market pullback (if you can call 1% a pullback) is all but a memory as stocks surged on Monday, with the S&P 500 hitting an intraday record high along with the Nasdaq notching another new record close. Helping positive sentiment was the U.S. FDA granting full approval to the COVID-19 vaccine developed by Pfizer Inc and its partner BioNTech SE. Investors were also looking ahead to the Federal Reserve’s Jackson Hole symposium, which gets underway later this week. Energy led the way among S&P 500 sectors, rising 3.8% as crude prices rose about 5%, snapping its 7-day losing streak from last week, while defensive sectors such as utilities lagged. In Asian markets, The Nikkei Index jumped 237 points to 27,732, the Shanghai Index gains 37 points to 3,514 and the Hang Seng Index jumps 618 points to 25,727. In Europe, the German DAX rises over 50 points above 15,900, while the FTSE 100 is down a few points holding around the 7,100 level. The big event for markets this week will take place in Jackson Hole at the economic symposium of the Federal Reserve. While some officials have stated plans to scale back stimulus, threats from the Delta variant have raised questions about whether they will hold off on signaling a taper timeline on $120B/month in bond buying. Market Closing Prices Yesterday The S&P 500 Index jumped 37.86 points, or 0.85%, to 4,479.53 The Dow Jones Industrial Average rose 215.63 points, or 0.61%, to 35,335.71 The Nasdaq Composite spiked 227.99 points, or 1.55%, to 14,942.65 The Russell 2000 Index advanced 40.70 points, or 1.88% to 2,208.30 Events Calendar for Today 7:45 AM ET ICSC Weekly Retail Sales 8:55 AM ET Johnson/Redbook Weekly Sales 4:30 PM ET API Weekly Inventory Data 10:00 AM ET New Home Sales MoM for July 10:00 AM ET Richmond Fed Manufacturing for Aug Earnings Calendar: Earnings Before the Open: AAP, CTRN, IMBI Earnings After the Close: ELMD, HEI, INTU, JWN, PSEC, SCSC, TOL, URBN, XPOF Other Key Events: American Association of Neurological Surgeons, 8/21-8/25, in Orlando, FL UBS China Telco, Media, Internet Virtual Conference 2021, 8/23-8/27 Truist Texas Bank Virtual Summit, 8/23-8/24 Craig Hallum Online Gaming Conference 8/24 Piper Sandler MedTech and Diagnostics California Bus Tour (virtual), 8/24-8/26 Raymond James Diversified Industrials Virtual Conference, 8/24-8/25 Macro Up/Down Last Nymex 1.10 66.74 Brent 1.23 69.98 Gold -0.30 1,805.15 EUR/USD -0.0006 1.1739 JPY/USD 0.03 109.73 10-Year Note +0.012 1.267% World News The House of Representatives scrapped a planned vote on Monday to advance two key economic proposals of President Biden’s $4.1T economic agenda. The chamber will reconvene at 12 p.m. ET today Sector News Breakdown Consumer Advance Auto Parts ($AAP) Q2 adj EPS $3.40 vs. est. $3.03; Q2 revs $2.6B vs. est. $2.62B; Q2 comp store sales +5.8%; increased full year 2021 guidance as now sees FY comparable store sales up 6.0% to 8.0% (from 4%-6%) and raises year sales view to $10.6B-$10.8B (from $10.4B-$10.6B) Mister Car Wash ($MCW) announces 12M share offering of common stock for holders Camping World ($CWH) raises quarterly dividend 100% to 50c from 25c per share Energy, Industrials and Materials International Flavors & Fragrances ($IFF) signed a deal to sell its microbial control unit to German specialty chemicals maker Lanxess, with the deal being valued at $1.3 billion, the companies said. Ferroglobe (GSM) Q2 EPS 2c vs. (7c) last year; Q2 revs $418.5M vs. $250.0M last year; Adjusted EBITDA of $34.1M, up 54.5% compared to $22.1M in Q1 2021; Positive operating cash flow of $37.8M and a return to positive net cash flow of $21.6M S.-listed energy shares rise premarket for a second day, mirroring strength in oil prices as hopes of improved coronavirus vaccination rates buoy energy’s demand outlook, after WTI crude snapped its 7-day losing streak yesterday The Federal Aviation Administration, or FAA, is launching a review of how Boeing ($BA) employees handle safety matters following a survey that found 35% of a small sample of employees reported issues with undue pressure and difficulties being transparent with regulators – WSJ Financials Riot Blockchain ($RIOT) Q2 EPS 22c vs. est. 5c; Q2 revs $31.5M vs. est. $30.91M; Q2 total cash and Bitcoin of $195.4M as of June 30; Increased mining revenue margin to 70% for the three-month period ended June 30, 2021, as compared to 25% for the same three-month period in 2020 Banco Santander SA said Tuesday that its U.S. subsidiary Santander Holdings USA, Inc. will acquire the remaining shares it doesn’t already own in Santander Consumer USA Holdings Inc. ($SC) for roughly $2.5 billion; Santander Holdings USA will buy the outstanding shares in Santander Consumer USA Holdings for $41.50 apiece via an all-cash tender offer https://bit.ly/3jchUiZ Healthcare Cigna ($CI) announces $2B accelerated buyback Cara Therapeutics ($CARA) shares rise after the company and Switzerland’s Vifor announced U.S. FDA approval for Korsuva kidney disease drug Theravance Biopharma, inc. (TBPH) announces top-line results from phase 2b dose-finding induction study of Izencitinib in patients with ulcerative colitis. Izencitinib was well-tolerated and safety data were consistent with expectations for this gut-selective pan-jak inhibitor. Randomized, double-blind, placebo-controlled study did not meet primary endpoint: change in total mayo score at week eight, vs placebo At least six U.S. states, including Georgia, have decided they will not fully sign on to a proposed $26 billion settlement with three drug distributors ($ABC, $CAH, $MCK) and Johnson & Johnson ($JNJ), which have been accused of fueling the nation’s opioid epidemic, according to the states’ attorneys general – Reuters Technology, Media & Telecom Palo Alto Networks ($PANW) Q4 adj EPS $1.60 vs. est. $1.43; Q4 revenue $1.2B vs. est. $1.17B; Q4 billings +34% to $1.9B; guides 1Q adj EPS $1.55-1.58 vs est. $1.59, sees 1Q revs +26-28% vs est. 21% and total billings $1.29-1.31B; guides FY22 adj EPS $7.15-7.25 vs est. $7.07, sees FY revs +24-25% vs est. +18.4% and billings $6.60-6.65B China stocks rebound ($BABA, $JD, $TCHEY, $BIDU) as Bloomberg reported Cathie Wood joins bargain hunters as Ark bought back into JD.com (JD) and Tencent Holdings ($TCEHY) shares rise after the company bought back 230,000 shares for HK$100.9 mln ($12.95 mln) on Aug. 23, according to HK Exchange filing https://bloom.bg/2WcxBy5 Tencent Holdings ($TCEHY) shares rise after the company bought back 230,000 shares for HK$100.9 mln ($12.95 mln) on Aug. 23, according to HK Exchange filing Crowdstrike ($CRWD) to replace Maxim Integrated ($MXIM) in the Nasdaq-100 Aug 26th The U.S. Securities and Exchange Commission (SEC) has started to issue new disclosure requirements to Chinese companies seeking to list in New York as part of a push to boost investor awareness of the risks involved, according to a document reviewed by Reuters and people familiar with the matter

Monday, June 21, 2021 Futures Up/Down % Last Dow 190.00 0.57% 33,345 S&P 500 18.0 0.43% 4,171 Nasdaq 61.75 0.44% 14,096 U.S. stock futures are looking sharply higher, tracking gains in Europe while Asian markets decline with global stock markets mixed. Stocks ended lower last week after the Federal Reserve said Wednesday it expects to raise interest rates by late 2023, sooner than previously projected. Prompting the policy shift was a much stronger economic rebound and hotter inflation than the Fed anticipated just a few months ago. Markets then again dropped on Friday after St. Louis Fed President James Bullard said during a TV interview on CNBC that inflation risks may warrant the Federal Reserve beginning raising interest rates next year, backing an even-earlier liftoff than penciled in by many of his colleagues. Shares of banks, energy firms and other companies that tend to be sensitive to the economy’s fluctuations have fallen sharply since the Fed’s meeting on Wednesday. Material stocks plunged with Nucor (NUE) falling ~13% in tough week for steel stocks, while Freeport-McMoRan (FCX) fell 14%, and gold miner Newmont Corp (NEM) dropped 11%. The S&P 500 Banks index plunges 8% as the yield curve flattens and energy stocks fall over 5% as crude retreats from multi-year highs as U.S. dollar firms after Fed signal on rates. Treasury yields plunged further overnight as the benchmark 10-year U.S. yield fell to its lowest since Feb. 24 at 1.354%, before recovering back to 1.433% now. Bitcoin prices dropping nearly 8% to $32,700, while Ethereum falls about 10% to $1,975 in a general rout of crypto assets to start the week; Bitcoin cash (BCH) down over 11% under $500 – crypto assets fall as Reuters reports further crackdown in China as authorities in the southwest province of Sichuan on Friday ordered cryptocurrency mining projects to close. In Asian markets, The Nikkei Index plunged -953 points to 28,010, the Shanghai Index was up a few points at 3,529 and the Hang Seng Index dropped -312 points to 28,489. In Europe, the German DAX is higher by 115 points to 15,560, while the FTSE 100 is up about 15 points to 7,030. Market Closing Prices Yesterday The S&P 500 Index dropped -55.41 points, or 1.31%, to 4,166.45 The Dow Jones Industrial Average fell -533.32 points, or 1.58%, to 33,290.08 The Nasdaq Composite slumped -131.02 points, or 0.93%, to 14,030.38 The Russell 2000 Index plunged -49.71 points, or 2.17% to 2,237.75 Events Calendar for Today 8:30 AM EST National Activity Index for May Earnings Calendar: Earnings Before the Open: PLUG Earnings After the Close: none Other Key Events: Goldman Sachs 17th Business Services, Transport & Leisure Conference (virtual), 6/21-6/23 Raymond James Human Health Innovation Conference (virtual), 6/21-6/23 Roth London Conference (virtual), 6/21-6/23 Macro Up/Down Last Nymex 0.17 71.81 Brent 0.06 73.57 Gold 15.20 1,784.20 EUR/USD 0.0032 1.1896 JPY/USD -0.13 110.08 10-Year Note -0.014 1.436% World News Bitcoin prices dropping nearly 8% to $32,700, while Ethereum falls about 10% to $1,975 in a general rout of crypto assets to start the week; Bitcoin cash (BCH) down over 11% under $500 – crypto assets fall as Reuters reports further crackdown in China as authorities in the southwest province of Sichuan on Friday ordered cryptocurrency mining projects to close. Negotiators for Iran and six world powers on Sunday adjourned talks on reviving their 2015 nuclear deal and return to respective capitals for consultations as remaining differences still need to be overcome, officials said – Reuters Sector News Breakdown Consumer Six Flags Entertainment (SIX) could keep climbing as it offers outdoor entertainment that’s close to home, according to Barron’s. Some 1.3 million people visited its parks in the first quarter, versus Wall Street’s estimate of just 600,000, boding well for the summer season when all of its North America parks will be open. Still, labor shortages could be a headwind. Porsche AG (POAHY) will develop and produce battery cells for electric sportscars in a new joint venture with German lithium-ion specialist Custom Cells GmbH; is investing a high double-digit million-euro sum and will control a 83.75% stake in the Cellforce venture Amazon (AMZN) Prime Day has kicked off, with the online retail giant promising more than 2 million deals over the two-day event. Energy, Industrials and Materials CNH Industrial (CNHI) agreed to acquire Raven Industries (RAVN) for $58.00 per share, in a transaction valued at $2.1B https://bit.ly/3iXZByo Chevron (CVX) said it was returning offshore workers who had been evacuated ahead of Tropical Storm Claudette from its Gulf of Mexico production platforms Boeing’s (BA) 737-10, the largest airplane in the 737 MAX family, completed a successful first flight on June 18. The airplane took off from Renton Field in Renton, Washington, at 10:07 a.m. and landed at 12:38 p.m. at Boeing Field in Seattle FedEx (FDX) mentioned positively in Barron’s saying it can charge higher fees when demand strengthens, thanks to the duopoly it shares with UPS (UPS), and that should add up to a strong earnings report this coming week. A big beat and strong guidance will probably be needed to move the stock higher Healthcare Tarsus Pharmaceuticals Inc. (TARS) said a pivotal Phase 2b/3 study of its investigational therapeutic TP-03 met all of its primary and secondary endpoints in patients with Demodex blepharitis, an ocular disease caused by an infestation of Demodex mites. Theravance Biopharma Inc. (TBPH) said its Phase 2 trial of its treatment for acute lung injury and impaired oxygenation didn’t meet its primary endpoint when compared with a placebo Technology, Media & Telecom Oracle (ORCL) mentioned positively in Barron’s saying the company is in the middle of a major business overhaul, reinventing itself for the cloud, and thought the stock has been among the year’s best performing tech shares, but the rally may not be over Pershing Square Tontine Holdings (PSTH), a special purpose acquisition company, announced that it had entered into a definitive agreement with Vivendi (VIVHY) to acquire 10% of the outstanding Ordinary Shares of Universal Music Group for approximately $4 billion

$TBPH Added to our buy at market/watchlist for tomorrow